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Introducción. El envejecimiento poblacional ha desplegado un nuevo y amplio campo de estudio para la ciencia sanitaria en el que la enfermería debe investigar para garantizar la autonomía en salud de las personas mayores. Objetivo: Visibilizar los Centros de Día Gerontológicos (CDG) y las actividades de los profesionales de enfermería en dichos centros en Huelva. Metodología: Se ha realizado una investigación cualitativa a partir de cuestionarios y entrevistas dirigidas al personal de dirección y enfermería de varios Centros de Día de Huelva y provincia. Resultados: Los CDG son un recurso intermedio con múltiples objetivos y funciones, que ofrecen calidad de vida tanto para los mayores como para sus familiares. Se componen de un equipo básico de profesionales que trabaja de forma no permanente. La figura de la enfermería es esencial, pero cuenta con una situación laboral muy deficiente. Conclusión: Estos centros proporcionan cuidados profesionales y permiten la permanencia en los domicilios habituales favoreciendo la calidad de vida y autonomía de esta población mayor. La bibliografía sobre este tema es escasa, por lo que se considera necesario profundizar en su investigación junto con la puesta en marcha de programas y propuestas de mejora que den a conocer estos centros sociosanitarios.
Objeto del presente ensayo reflexivo: mostrar y reflexionar sobre la utilidad que tiene la investigación cualitativa y/o fenomenológica en la atención del paciente que presenta diabetes. Desarrollo: la atención integral de una forma biopsicosocial, cultural y espiritual tanto al paciente como a la familia del mismo por parte del profesional sanitario, juega un papel importante a la hora de tener calidad de vida en el nuevo estilo de vida. Conclusiones y reflexiones finales: La investigación cualitativa en enfermería, ayuda a interpretar el sufrimiento del paciente, su relación con su entorno social y cultural y sus sentimientos e inquietudes dentro de la diabetes.
Epilepsy is a common neurological disorder characterised by recurrent seizures. Almost half of patients who have an unprovoked first seizure (UFS) have additional seizures and develop epilepsy. No current predictive models exist to determine who has a higher risk of recurrence to guide treatment. Emerging evidence suggests alterations in cognition, mood and brain connectivity exist in the population with UFS. Baseline evaluations of these factors following a UFS will enable the development of the first multimodal biomarker-based predictive model of seizure recurrence in adults with UFS.
200 patients and 75 matched healthy controls (aged 18–65) from the Kingston and Halifax First Seizure Clinics will undergo neuropsychological assessments, structural and functional MRI, and electroencephalography. Seizure recurrence will be assessed prospectively. Regular follow-ups will occur at 3, 6, 9 and 12 months to monitor recurrence. Comparisons will be made between patients with UFS and healthy control groups, as well as between patients with and without seizure recurrence at follow-up. A multimodal machine-learning model will be trained to predict seizure recurrence at 12 months.
This study was approved by the Health Sciences and Affiliated Teaching Hospitals Research Ethics Board at Queen’s University (DMED-2681-22) and the Nova Scotia Research Ethics Board (1028519). It is supported by the Canadian Institutes of Health Research (PJT-183906). Findings will be presented at national and international conferences, published in peer-reviewed journals and presented to the public via patient support organisation newsletters and talks.
Objetivo. Describir los registros enfermeros sobre heridas quirúrgicas en pacientes intervenidos en una unidad de Cirugía General y Digestiva. Metodología. Estudio descriptivo transversal. Se revisaron las historias clínicas electrónicas de adultos hospitalizados en una Unidad de Cirugía General y Digestiva que tuvieron una herida quirúrgica durante su estancia en el hospital. Se revisó la documentación de las heridas quirúrgicas en el registro específico de heridas, las notas de los evolutivos de enfermería, los planes de cuidados y el informe de continuidad de cuidados (alta de enfermería). Resultados: muestra de 200 pacientes con una edad media de 58,24 (±17,12) años. En ningún caso se documentó la herida quirúrgica utilizando el registro específico. Las heridas sí se documentaron en las notas del evolutivo de enfermería, con comentarios sobre realización de curas en el 85,5% de los pacientes y sobre el estado o valoración de la herida en el 41%. En el plan de cuidados no se programó ninguna actividad sobre el cuidado de la herida quirúrgica en el 48% de los casos y en el informe de continuidad de cuidados no se refleja la evaluación de la herida quirúrgica en el 85,5% de los casos. Discusión. El registro de las heridas quirúrgicas se realiza de forma incompleta, desigual y poco sistemática, sin utilizar registros específicos estructurados. Detectando las deficiencias de los registros enfermeros sobre las heridas quirúrgicas podemos plantear estrategias para mejorarlos y así incrementar la calidad y seguridad de los cuidados postquirúrgicos.
ABSTRACT
Objective. To describe nursing records of surgical wounds in patients who underwent surgery in a General and Digestive Surgery Department. Methodology. Cross-sectional descriptive study. Electronic medical records of adult inpatients admitted to a General and Digestive Surgery Department who had a surgical wound during their hospital stay were reviewed. Documentation of surgical wounds in the specific wound register, nursing progress notes, care plans and continuity of care reports (nursing discharge reports) were reviewed. Results. 200 patients with a mean age of 58.24 (±17.12) years were analyzed. There were no surgical wounds documented using the specific register. However, they were documented in the nursing progress notes, with comments on wound/dressing management and wound status or assessment in 85.5% and 41% of patients, respectively. No activity on surgical wound care was scheduled in the 48% of care plans, and surgical wound assessment was not included in the 85,5%m of the continuity of care reports. Discussion. Surgical wound documentation is performed in a incomplete, inconsistent and unsystematic way, without using specific structured registers. By identifying deficiencies in nursing records of surgical wounds, we would be able to suggest strategies to improve them and, therefore, to increase the quality and safety of post-surgery care.
Patient engagement is the active collaboration between patient partners and health system partners towards a goal of making decisions that centre patient needs—thus improving experiences of care, and overall effectiveness of health services in alignment with the Quintuple Aim. An important but challenging aspect of patient engagement is including diverse perspectives particularly those experiencing health inequities. When such populations are excluded from decision-making in health policy, practice and research, we risk creating a healthcare ecosystem that reinforces structural marginalisation and perpetuates health inequities.
Despite the growing body of literature on knowledge coproduction, few have addressed the role of power relations in patient engagement and offered actionable steps for engaging diverse patients in an inclusive way with a goal of improving health equity. To fill this knowledge gap, we draw on theoretical concepts of power, our own experience codesigning a novel model of patient engagement that is equity promoting, Equity Mobilizing Partnerships in Community, and extensive experience as patient partners engaged across the healthcare ecosystem. We introduce readers to a new conceptual tool, the Power Wheel, that can be used to analyse the interspersion of power in the places and spaces of patient engagement.
As a tool for ongoing praxis (reflection +action), the Power Wheel can be used to report, reflect and resolve power asymmetries in patient-partnered projects, thereby increasing transparency and illuminating opportunities for equitable transformation and social inclusion so that health services can meet the needs and priorities of all people.
This study aimed (1) to examine the association between patient engagement with a bidirectional, semiautomated postdischarge texting programme and Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey outcomes, readmissions and revisit rates in a large health system and (2) to describe operational and clinical flow considerations for implementing a postdischarge texting programme.
The study involved 1 main academic hospital (beds: 2500+) and 6 community hospitals (beds: 190–400, averaging 300 beds per hospital) in Houston, Texas.
Retrospective, observational cohort study between non-engaged patients (responded with 0–2 incoming text messages) and engaged patients (responded with 3+ incoming, patient-initiated text messages) between December 2022 and May 2023. We used the two-tailed t-test for continuous variables and 2 test for categorical variables to compare the baseline characteristics between the two cohorts. For the binary outcomes, such as the revisit (1=yes, vs 0=no) and readmissions (1=yes vs 0=no), we constructed mixed effect logistic regression models with the random effects to account for repeated measurements from the hospitals. For the continuous outcome, such as the case mix index (CMI), a generalised linear quantile mixed effect model was built. All tests for significance were two tailed, using an alpha level of 0.05, and 95% CIs were provided. Significance tests were performed to evaluate the CMI and readmissions and revisit rates.
From 78 883 patients who were contacted over the course of this pilot implementation, 49 222 (62.4%) responded, with 39 442 (50%) responded with 3+ incoming text messages. The engaged cohort had higher HCAHPS scores in all domains compared with the non-engaged cohort. The engaged cohort used significantly fewer 30-day acute care resources, experiencing 29% fewer overall readmissions and 20% fewer revisit rates (23% less likely to revisit) and were 27% less likely to be readmitted. The results were statistically significant for all but two hospitals.
This study builds on the few postdischarge texting studies, and also builds on the patient engagement literature, finding that patient engagement with postdischarge texting can be associated with fewer acute care resources. To our knowledge, this is the only study that documented an association between a text-based postdischarge programme and HCAHPS scores, perhaps owing to the bidirectionality and ease with which patients could interact with nurses. Future research should explore the texting paradigms to evaluate their associated outcomes in a variety of postdischarge applications.
To assess the effects of COVID-19 pandemic on clinical variables as part of the routine clinical monitoring of patients with chronic diseases in primary care.
A prospective longitudinal study was conducted in primary care centres of the Andalusian Health Service.
Data were recorded before the pandemic (T1), during the declaration of the state of emergency (T2) and in the transition phase (T3). The Barthel index and the Short Portable Mental Status Questionnaire (SPMSQ) were used to analyse functional and cognitive changes at the three time points. HbA1c, systolic and diastolic blood pressure, heart rate, BMI and lipid levels were assessed as clinical variables. Descriptive statistics and non-parametric chi-square test were used for analysis. STROBE checklist was used for the preparation of this paper.
A total fo148 patients with chronic conditions were included in the analysis. Data analysis revealed in T2 only significant reductions in BMI, total levels of cholesterol and HDL during the onset of the pandemic. Barthel Index, SPMSQ, blood pressure and triglycerides and LDL levels worsened in T2, and the negative effects were maintained in T3. Compared to pre-pandemic values, HbA1c levels improved in T3, but HDL levels worsened.
COVID-19 has drastically disrupted several functional, cognitive and biological variables. These results may be useful in identifying clinical parameters that deserve closer attention in the case of a new health crisis. Further studies are needed to assess the potential impacts of each specific chronic condition.
Cognitive and functional status, blood pressure and triglycerides and LDL levels worsen in short term, maintaining the negative effects in medium-term.
To evaluate the impact of nurse care changes in implementing a blood pressure management protocol on achieving rapid, intensive and sustained blood pressure reduction in acute intracerebral haemorrhage patients.
Retrospective cohort study of prospectively collected data over 6 years.
Intracerebral haemorrhage patients within 6 h and systolic blood pressure ≥ 150 mmHg followed a rapid (starting treatment at computed tomography suite with a target achievement goal of ≤60 min), intensive (target systolic blood pressure < 140 mmHg) and sustained (maintaining target stability for 24 h) blood pressure management plan. We differentiated six periods: P1, stroke nurse at computed tomography suite (baseline period); P2, antihypertensive titration by stroke nurse; P3, retraining by neurologists; P4, integration of a stroke advanced practice nurse; P5, after COVID-19 impact; and P6, retraining by stroke advanced practice nurse. Outcomes included first-hour target achievement (primary outcome), tomography-to-treatment and treatment-to-target times, first-hour maximum dose of antihypertensive treatment and 6-h and 24-h systolic blood pressure variability.
Compared to P1, antihypertensive titration by stroke nurses (P2) reduced treatment-to-target time and increased the rate of first-hour target achievement, retraining of stroke nurses by neurologists (P3) maintained a higher rate of first-hour target achievement and the integration of a stroke advanced practice nurse (P4) reduced both 6-h and 24-h systolic blood pressure variability. However, 6-h systolic blood pressure variability increased from P4 to P5 following the impact of the COVID-19 pandemic. Finally, compared to P1, retraining of stroke nurses by stroke advanced practice nurse (P6) reduced tomography-to-treatment time and increased the first-hour maximum dose of antihypertensive treatment.
Changes in nursing care and continuous education can significantly enhance the time metrics and blood pressure outcomes in acute intracerebral haemorrhage patients.
STROBE guidelines.
No Patient or Public Contribution.
To analyse the influence of the COVID-19 pandemic and the perception of self-efficacy on the health professionals of the Spanish out-of-hospital emergency services.
Observational, cross-sectional and descriptive with a survey methodology of 1710 participants from Spain (1 February–30 April, 2021).
The mental health of healthcare workers was assesed in terms of stress, anxiety and depression, as well as their self-efficacy. Linear and logistic regression models were fitted to predict these variables. A moderation analysis was conducted to determine the effect of self-efficacy on mental health.
The means of the sample for stress, anxiety, depression and self-efficacy were 20.60, 15.74, 13.07 and 70.87, respectively. In the regression models, being a woman was the most significant factor for severe mental health impairment. Female gender was also a relevant factor for self-efficacy. Self-efficacy had a direct effect on the mental health for working in patient care.
Healthcare workers showed moderate stress, severe anxiety, mild depression and good self-efficacy. Direct patient care was associated with more stress and severe anxiety. Age, female gender, job changes and job adjustment were associated with levels of stress, anxiety and depression. Self-efficacy is a determining factor of mental health in the direct care modality.
The mental health of healthcare workers has been of great importance in the aftermath of the pandemic, but out-of-hospital emergency workers have been neglected in research. The levels of stress, anxiety and depression during the pandemic justify the creation of prevention and early diagnosis programmes, as they are essential in a health disaster. Surprisingly, their high level of perceived self-efficacy directly impact on the mental health of patient helthcare workers, so improving it will reduce the psychological risk.
We have followed the STROBE guidelines. It has been partially funded by the Asistencia Sanitanitaria Interprovincial de Seguros - ASISA Foundation (Spain).
‘No patient or public involvement’.
To explore adverse event reporting in the surgical department through the nurses' experiences and perspectives.
An exploratory, descriptive qualitative study was conducted with a theoretical-methodological orientation of phenomenology.
In-depth interviews were conducted with 15 nurses, followed by an inductive thematic analysis.
Themes include motives for reporting incidents, consequences, feelings and motivational factors. Key facilitators of adverse event reporting were effective communication, knowledge sharing, a non-punitive culture and superior feedback.
The study underscores the importance of supportive organisational culture for reporting, communication and feedback mechanisms, and highlights education and training in enhancing patient safety.
It suggests the need for strategies that foster incident reporting, enhance patient safety and cultivate a supportive organisational culture.
This study provides critical insights into adverse event reporting in surgical departments from nurses' lived experience, leading to two primary impacts: It offers specific solutions to improve adverse event reporting, which is crucial for surgical departments to develop more effective and tailored reporting strategies. The research underscores the importance of an open, supportive culture in healthcare, which is vital for transparent communication and effective reporting, ultimately advancing patient safety.
The study followed the Standards for Reporting Qualitative Research and the Consolidated Criteria for Reporting Qualitative Research guidelines.
No patients or public contribution.
Introducción. La prevalencia de obesidad infantil se ha incrementado de forma considerable desde el año 2000 adquiriendo la dimensión de epidemia, al presentar el 5,9% de los niños menores de 5 años sobrepeso. Entre los factores causantes modificable se encuentran el estilo de vida, sueño, dieta y actividad física. El objetivo es evaluar la eficacia de una intervención educativa en entorno escolar para la modificación de hábitos de niños de 6-12 años en 3 áreas, dieta, actividad física y tiempo de pantalla. Metodología. La muestra es de 540 niños, en etapa de educación primaria distribuida, en tres grupos: a) intervención dieta y tiempo de pantalla, b) actividad física y tiempo de pantalla y, c) dieta, actividad física y tiempo de pantalla. La intervención educativa incluye contenidos del método plato, pirámide de alimentación y ejercicio basados en la guía canadiense de actividad física para niños de 5-11 años. Se recopilan variables de edad y medidas antropométricas. En instrumentación se considera el Test KIDMED (adherencia a dieta), Cuestionario “IPAQ-A” (actividad física), cuestionario tiempo de pantalla (uso dispositivos electrónicos). La recopilación de datos se realiza pre-intervención, post-intervención y al mes de finalización de la intervención. El análisis considera estadística descriptiva para la distribución y valores de las variable cuantitativas y cualitativas y, estadística analítica para el análisis de la eficacia la intervención según corresponda al tipo de variable tales como la prueba de t de Student, ANOVA, Chi cuadrado, prueba de Correlación de Pearson. Los datos serán analizados con el sistema estadístico SPSS.
ABSTRACT
Introduction. The prevalence of childhood obesity has increased considerably since 2000, acquiring the dimension of an epidemic, with 5.9% of children under 5 years of age being overweight. Modifiable causative factors include lifestyle, sleep, diet and physical activity. The objective is to evaluate the effectiveness of an educational intervention in a school environment to modify the habits of children aged 6-12 years in 3 areas, diet, physical activity and screen time. Methodology. The sample is 540 children, in primary education stage distributed, in three groups: a) diet and screen time intervention, b) physical activity and screen time and c) diet, physical activity and screen time. The educational intervention includes contents of the plate method, food pyramid and exercise based on the Canadian physical activity guide for children aged 5 to 11 years. Age variables and anthropometric measurements are collected. In instrumentation, the KIDMED Test (diet adherence), “IPAQ-A” Questionnaire (physical activity), and screen time questionnaire (use of electronic devices) are considered. Data collection is carried out pre-intervention, post-intervention and one month after the end of the intervention. The analysis considers descriptive statistics for the distribution and values of the quantitative and qualitative variables and analytical statistics for the analysis of the effectiveness of the intervention as appropriate to the type of variables such as Student's t test, ANOVA, Chi square, Pearson correlation. The data will be analyzed with the SPSS statistical system.
Resumen:
Introducción. El uso en pediatría de adhesivos tisulares como el cianocrilato para el cierre de heridas ofrece ventajas significativas. Es un procedimiento sencillo rápido e indoloro, conformándose como una alternativa en la población pediátrica debido a las características específicas de estos pacientes. Objetivo. Evaluar la efectividad del adhesivo tisular con cianocrilato en el cierre de heridas en zonas pilosas y mentón. Metodología. Se diseñó un estudio observacional prospectivo conformado por pacientes pediátricos que acudieron a urgencias con heridas que requerían sutura en zona mentoniana, ceja y cuero cabelludo. Se valoraron variables demográficas y clínicas, así como la colaboración del menor y grado de satisfacción de padres y profesionales tras la aplicación de cianocrilato. A los 3 meses se valoró la cicatrización. Los datos se analizaron mediante el programa estadístico SSPS. Resultados. Las heridas en zonas pilosas presentaron una correcta epitelización con un índice ≤ 2 según escala de Vancouver. Se establecieron diferencias estadísticamente significativas entre la localización de la herida y su cicatrización (p<0.05). Se objetivó un grado de concordancia moderado entre la satisfacción de los padres y los profesionales con un p-valor < 0.001. Discusión. Los adhesivos tisulares con base de cianocrilato parecen una alternativa válida y segura para la reparación de heridas en zonas con folículo piloso. Cuenta con la aprobación de pacientes, familiares y profesionales que realizaron el procedimiento. Los resultados respecto a la cicatrización evaluados a los 3 meses son más satisfactorios en áreas pilosas.
ABSTRACT
Introduction. The use of tissue adhesives like cyanoacrylate for wound closure in pediatrics offers significant advantages. It is a simple, fast, and painless procedure, making it an alternative in the pediatric population due to the specific characteristics of these patients. Objective. To evaluate the effectiveness of tissue adhesive with cyanoacrylate in closing wounds on the scalp or hairy areas and the chin region. Methodology. A prospective observational study was designed, consisting of pediatric patients who presented to the emergency department with wounds requiring sutures in the chin, eyebrow, and scalp areas. Demographic and clinical variables were assessed, as well as the cooperation of the child and the satisfaction level of parents and healthcare professionals after the application of cyanoacrylate. Scar healing was assessed at 3 months. Data were analyzed using the statistical software SPSS. Results. Wounds in hairy areas showed proper epithelialization with an index ≤2 according to the Vancouver scale. Statistically significant differences were found in the relationship between wound location and its healing (p<0.05). Additionally, a moderate level of agreement was observed between parent and professional satisfaction, with a p-value <0.001. Discusión. Cyanoacrylate-based tissue adhesives appear to be a valid and safe alternative for wound repair in areas with hair follicles. They are well-received by patients, their families, and the professionals who performed the procedure. The results regarding scar healing evaluated at 3 months are more satisfactory on the scalp and eyebrow compared to the chin region.
This paper aims to examine the satisfaction and depressed mood experienced by nursing home workers during the COVID-19 pandemic and associated variables. Specifically, to analyse the factors that may contribute to nursing home workers developing adaptive behaviours that promote satisfaction or, on the contrary, show characteristics associated with a negative mood.
Nursing homes have faced unprecedented pressures to provide appropriately skills to meet the demands of the coronavirus outbreak.
A cross-sectional survey design using the STROBE checklist.
Professionals working in nursing homes (n = 165) completed an online survey measuring sociodemographic and professional characteristics, burnout, resilience, experiential avoidance, satisfaction with life and depression. Data were collected online from April to July 2021, the time in which Spain was experiencing its fifth wave of COVID-19. Two multiple linear regression models were performed to identify salient variables associated with depressive mood and satisfaction.
Resilience, personal accomplishment and satisfaction had a significant and negative relationship with depression and emotional exhaustion, depersonalisation and experiential avoidance had a positive relationship with depression. However, emotional exhaustion, depersonalisation and experiential avoidance had a negative and significant relationship with satisfaction and personal accomplishment, and resilience had a positive and significant relationship with satisfaction. In addition, it was found that accepting thoughts and emotions when they occur is beneficial for developing positive outcomes such as satisfaction.
Experiential avoidance was an important predictor of the effects that the COVID-19 pandemic can have on nursing home workers.
Interventions focusing on resources that represent personal strengths, such as acceptance, resilience and personal accomplishment, should be developed.
The complex and unpredictable circumstances of COVID's strict confinement in the nursing home prohibited access to the centres for external personnel and family members. Contact with the professionals involved could not be made in person but exclusively through online systems. However, professionals related to the work environment have subsequently valued this research positively as it analyses ‘How they felt during this complicated process’.
This study aims to evaluate the Language Access Systems Improvement (LASI) initiative’s impact on professional interpreter utilisation in primary care and to explore patient and clinician perspectives on professional interpreter use.
Multi methods: Quantitative natural experiment pre-LASI and post-LASI, qualitative semistructured interviews with clinicians and focus groups with patients post-LASI.
Large, academic primary care practice.
Cantonese, Mandarin, Spanish, English-speaking adult patients and their clinicians.
LASI initiative: Implementation of a clinician language proficiency test and simultaneous provision of on-demand access to professional interpreters via video medical interpretation.
Quantitative: Proportion of language discordant primary care visits which were professionally interpreted. Qualitative: Salient themes related to professional interpreter use and non-use.
The researchers categorised language concordance for 1475 visits with 152 unique clinicians; 698 were not fully language concordant (202 pre-LASI and 496 post-LASI). Professional interpreter utilisation increased (pre-LASI 57% vs post-LASI 66%; p=0.01); the visits with the lowest percentage of profssional interpreter use post-LASI were those in which clinicians and patients had partial language concordance. In inverse probability weighted analysis, restricting to 499 visits with strict estimated propensity score overlap (100% common support), post-LASI visits had higher odds of using a professional interpreter compared with pre-LASI visits (OR 2.39; 95% CI 1.04 to 5.48). Qualitative results demonstrate video interpretation was convenient and well liked by both clinicians and patients. Some partially bilingual clinicians reported frustration with patient refusal of interpreter services; others reported using the video interpreters as a backup during visits. Views of the care-partner role differed for clinicians and patients. Clinicians reported sometimes having family interpret out of convenience or habit, whereas patients reported wanting family members present for support and advocacy, not interpretation.
LASI increased utilisation of professional interpreters; however, this was least prominent for partially language concordant visits. Health systems wishing to implement LASI or similar interventions will need to support clinicians and patients with partial bilingual skills in their efforts to use professional interpreters.
HSRP20153367.
The main objective of the study was to evaluate the influence of arterial hypertension, diabetes, dyslipidaemia, smoking, alcoholism and COPD (chronic obstructive pulmonary disease) on the viability of the extracted tissue as well as the donor.
Observational case–control study.
Regional hospital in Northern Spain.
1517 corneas were registered.
Patients’ medical history was reviewed after corneal donation and evaluation. Previous medical information (age, sex and cardiovascular risk factors (CVRFs)) and data related to the donor (type of donor), the corneal tissue and its evaluation, and the viability of the implant were collected.
A total of 1517 corneas were registered and 81.5% of the donors presented at least one CVRF. In relation to the viability of the donor, it was observed that having suffered from COPD reduced the viability of the donor (no COPD: 93.8% vs COPD: 88%; OR=0.49; 95% CI: 0.28 to 0.84) while alcohol consumption increased it (drinker or ex-drinker: 95.8% vs non-drinker: 92.5%; OR=1.84; 95% CI: 1.01 to 3.33). Regarding tissue viability, decreased viability was observed in the presence of COPD (no COPD: 72.5% vs COPD: 64; OR=0.67; 95% CI: 0.47 to 0.96) and diabetes mellitus (no diabetes: 72.9% vs diabetes: 67.2%; OR=0.76; 95% CI: 0.58 to 0.99). As regards the viability of the implant, a total of 1039 corneas (68.9%) were suitable, observing decreased viability when suffering from COPD (no COPD: 69.8% vs COPD: 60.7%; OR=0.67; 95% CI: 0.47 to 0.94) and increased when having an active smoking habit (no habit: 65.3% vs habit: 74.1%; OR=1.52; 95% CI: 1.21 to 1.91).
Through this study, it can be concluded that in the absence of absolute exclusion criteria for donors, the assessment of how CVRF, alcoholism and COPD may affect the donor provides details about the quality of the tissue to be obtained.
by Patricia Escobedo, Daniel Garcia, Liam Cascelli, Gabriela Chavira, Gilberto E. Flores, Jodi L. Constantine Brown, David Boyns, Andrew T. Ainsworth
In March 2020, the COVID-19 pandemic forced many in person undergraduate research experiences (UREs) to pivot to remote online training. To investigate how the COVID-19 quarantine disrupted student URE outcomes over time, the current study examines Building Infrastructure Leading to Diversity (BUILD) Promoting Opportunities for Diversity in Education and Research (PODER) URE outcomes across different platforms (in-person, remote, and hybrid models) by comparing student survey data from 2019 to 2021. Participants consisted of three cohorts: 2019 (n = 26 students), 2020 (n = 33), 2021 (n = 34). The BUILD PODER Summer JumpStart program (SJS), which aims to increase diversity in Science, Technology, Engineering, and Mathematics (STEM) by recruiting mostly underrepresented students, was conducted in person in 2019, remotely in 2020 and using a hybrid model in 2021. All students completed an online survey on the first and last day of the four-week SJS program. We used one-way and mixed ANOVA models to analyze Cohort, Time (pre-test vs. post-test scores), and interaction of Cohort and Time for Research Self-Efficacy, Sense of Belonging, Mentor Relationship, Mentee Knowledge, Health, Stress, and Student Program Satisfaction measures. Despite the platform changes, student scores increased significantly over time for all measures. There was a significant main effect of Time for Research Self-Efficacy, Sense of Belonging, Mentor Relationship, Mentee Knowledge, Health Assessment, and Stress Management. Findings indicate that URE programs that are implemented remotely and using a hybrid format can provide students with experiences similar to in-person URE programs. In addition, remote UREs may provide added benefits compared to in-person programs. For instance, remote UREs could engage more historically minoritized students, who may experience barriers to access, such as work/family commitments, financial constraints, and geographic limitations.This study aims to investigate the association of ulcerative colitis (UC) with all-cause dementia and assess differences in those with and without a total colectomy.
This Swedish prospective register-based study comprised 4.8 million individuals aged at least 59 years between 1964 and 2018 with the linkage of several Swedish national registers.
Individuals with dementia were defined according to International Classification of Diseases diagnostic codes and Anatomical Therapeutic Classification codes for medication prescriptions. Fitting Cox hazards models, the risk of developing all-cause dementia in individuals with and without UC was estimated. Further, we compared the risk of all-cause dementia among those with and without a colectomy.
Among 4 821 488 individuals (52.6% females) followed for 84.1 million person-years between 1964 and 2018, the incidence rate of all-cause dementia was 63.90 (63.73–64.07) events per 10 000 person-years in individuals without UC, 94.80 (92.04–97.64) among those with UC, 95.01 (92.25–97.86) in those with UC but without colectomy and 63.42 (40.92–98.31) in those with UC and a colectomy. Adjusted Cox models showed an increased all-cause dementia risk in individuals with UC (HR 1.07, 95% CI 1.04 to 1.10). We found no differences between unexposed individuals and those with UC and a colectomy (HR 0.89, 95% CI 0.57 to 1.38).
The findings are consistent with previous evidence suggesting a slightly increased dementia risk among individuals with UC. This study provided no evidence of further risk increase of dementia among those who had a colectomy.
Since 2019, the nursing profession has been frequently represented in mainstream media in the UK through the lenses of the COVID-19 pandemic and more recently, industrial action. In 2020, during COVID, we saw the nursing profession praised, with weekly neighbourhood applause and thanks to the National Health Service (NHS) staff schemes. In 2023, when, for the first time in history nurses voted to strike (fair pay for nursing), nurses again received media attention. Conversely, the media chose to report how striking nurses (and other health professional staff) contributed to long waiting lists in the NHS and unhelpfully, demonstrated how 64% of poll voters (n=7955) did not think nurses should have a better pay deal.
Over 40 million people in low-income and middle-income countries (LMICs) experience serious health-related suffering (SHS) annually and require palliative care. Patient and caregiver experiences of SHS in LMICs are understudied despite their importance in guiding palliative care provision. Diabetes and cancer are the second-leading and third-leading causes of death in Mexico, causing a significant SHS burden on patients, families and health systems. This study examines SHS and palliative care from the point of view of patients with cancer and diabetes and their caregivers.
A qualitative descriptive study based on in-depth telephone interviews was conducted between August 2021 and February 2022. Data were analysed through inductive thematic analysis.
Overall, 20 patients with end-stage cancer, 13 patients with diabetes and 35 family caregivers were interviewed individually.
Participants were recruited from two family medicine clinics and a pain clinic in Mexico City.
Seven themes emerged: (1) suffering as a multifaceted phenomenon, (2) diversity in perceptions of suffering, (3) different coping strategies, (4) need and perceived importance of relief from suffering, (5) barriers to accessing services to relieve suffering, (6) demand for the health sector’s active and humane role in addressing suffering and (7) preferences and need for comprehensive care for relief from suffering. The primary coping strategies included family companionship, protective buffering and faith-based support. Participants lacked knowledge of palliative care. They expressed the importance of relief from suffering, viewing it as the health sector’s responsibility and requesting more humane, personalised care and access to medicines and pain clinics.
The multifaceted nature of SHS highlights the health system’s responsibility to provide high-quality palliative care. Policies to enhance access to palliative care should integrate it into primary care, redesigning services towards patient and caregiver biopsychosocial and spiritual needs and ensuring access to medicines and competent health personnel.
This study aimed to evaluate the effectiveness, safety and costs of FreeStyle Libre (FSL) glucose monitoring system for children and adolescents with type 1 diabetes mellitus (T1DM) in Spain.
Prospective, multicentre pre-post study.
Thirteen Spanish public hospitals recruited patients from January 2019 to March 2020, with a 12-month follow-up.
156 patients were included.
Primary: glycated haemoglobin (HbA1c) change. Secondary: severe hypoglycaemic events (self-reported and clinical records), quality of life, diabetes treatment knowledge, treatment satisfaction, adverse events, adherence, sensor usage time and scans. Healthcare resource utilisation was assessed for cost analysis from the National Health System perspective, incorporating direct healthcare costs. Data analysis used mixed regression models with repeated measures. The intervention’s total cost was estimated by multiplying health resource usage with unit costs.
In the whole sample, HbA1c increased significantly (0.32%; 95% CI 0.10% to 0.55%). In the subgroup with baseline HbA1c≥7.5% (n=88), there was a significant reduction at 3 months (–0.46%; 95% CI –0.69% to –0.23%), 6 months (–0.49%; 95% CI –0.73% to –0.25%) and 12 months (–0.43%; 95% CI –0.68% to –0.19%). Well-controlled patients had a significant 12-month worsening (0.32%; 95% CI 0.18% to 0.47%). Self-reported severe hypoglycaemia significantly decreased compared with the previous year for the whole sample (–0.37; 95% CI –0.62 to –0.11). Quality of life and diabetes treatment knowledge showed no significant differences, but satisfaction increased. Adolescents had lower sensor usage time and scans than children. Reduction in HbA1c was significantly associated with device adherence. No serious adverse effects were observed. Data suggest that use of FSL could reduce healthcare resource use (strips and lancets) and costs related to productivity loss.
The use of FSL in young patients with T1DM was associated with a significant reduction in severe hypoglycaemia, and improved HbA1c levels were seen in patients with poor baseline control. Findings suggest cost savings and productivity gains for caregivers. Causal evidence is limited due to the study design. Further research is needed to confirm results and assess risks, especially for patients with lower baseline HbA1c.
FreshRSS 