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Prevalencia de úlceras por presión y factores asociados a su desarrollo en Acapulco Gro: estudio transversal

Objetivo principal: Determinar la prevalencia de úlceras por presión e identificar los factores asociados para su desarrollo en pacientes hospitalizados en el Hospital General Regional N°1 “Vicente Guerrero” del IMSS en Acapulco, Gro, México. Metodología: Estudio observacional, transversal, analítico, realizado con 256 pacientes en los diversos servicios del hospital, se midieron variables demográficas y clínicas, calculando frecuencias absolutas y relativas, Odds Ratio para medir la relación factor /evento, y análisis multivariado de regresión logística para controlar la variable de confusión. Resultados principales: La prevalencia de las UPP fue del 26.95%, el estadio I el más frecuente (55.1%). Los factores asociados al desarrollo de las UPP son: edad, días de estancia, servicio de Medicina Interna y padecer diabetes mellitus II. Conclusión principal: Los hallazgos de prevalencia son alarmantes comparados con el reporte nacional (20.07%), requiriendo una intervención inmediata de gestión de cuidado enfermero, resolviendo los riesgos y problemas asociados a la aparición de UPP.

Tengo apnea del sueño y dificultad para dormirme ¿Puedo tomar mi pastilla de dormir con la CPAP?

Objetivo principal: Comprobar la existencia de evidencia científica que avale o rechace el uso de sedantes/hipnoticos en pacientes que sufren apnea del sueño y usan una máquina de presión positiva continua en la vía aérea (CPAP) domiciliaria. Metodología: Revisión bibliográfica. Resultados principales: No existen estudios actuales con un buen nivel de evidencia que demuestren que el uso de hipnoticos/sedantes perjudique a los pacientes que usan CPAP. Conclusión principal: Sería beneficioso recomendar a los pacientes usuarios de CPAP que presenten problemas de insomnio el uso de hipnoticos/sedantes, siempre bajo prescripción médica y tras valoración del resto de patologías.

Cuidados de enfermería en prevención de mucositis oral secundaria al tratamiento oncológico: una revisión integrativa

Justificación: La mucositis oral es una complicación del tratamiento oncológico que tiene alto impacto en la calidad de vida de los pacientes que la padecen; es esencial que los cuidados de enfermería entregados estén dirigidos a prevenir y/o disminuir la gravedad de la mucositis oral y sean avalados con evidencia de su efectividad. Objetivo: Identificar los cuidados de enfermería dirigidos a prevenir la mucositis oral en pacientes oncológicos. Metodología: Revisión integrativa en 6 bases de datos de artículos publicados desde el año 2000 al 2015. Resultados principales: Los cuidados de enfermería encontrados son la intervención educativa en relación a técnicas de cepillado dental, higiene bucal, autoevaluación de la integridad de la mucosa a través de escalas y el uso de crioterapia durante la administración de citostáticos. Conclusión: Los cuidados de enfermería mencionados probaron su efectividad en la prevención de la aparición y severidad de la mucositis oral, además de ser costo-efectivas tanto en pacientes oncológicos pediátricos y adultos.

¿Influye la resiliencia en la salud mental de los profesionales de cuidados críticos y en dificultar el desarrollo del síndrome de Burnout?

El comentario crítico se estructuró siguiendo la propuesta de López Alonso et al.1 Se realizó una lectura crítica usando la lista de comprobación STROBE para estudios observacionales.2 Dado que la investigación observacional utiliza muchos diseños diferentes, nos centramos en los criterios específicos del diseño transversal [Fragmento de texto].

Estigmatización de la "falta" desde una perspectiva cultural: influencia de la infertilidad en la salud y actuaciones de Enfermería

Objetivo principal: Identificar la evidencia científica disponible sobre los diversos estigmas que provoca la infertilidad a diversos niveles en quien la padece. Metodología: Se realizó una búsqueda bibliográfica de los últimos diez años en las bases de datos PubMed, Web of Science y Cinahl. Resultados principales: Aunque a priori pudiera parecer que existen grandes diferencias culturales en la percepción de la infertilidad como fenó-meno a nivel íntimo, existen una serie de parámetros coincidentes en la gestión de este tipo de problemáticas por parte de los afectados, tales como la vergüenza, el sentimiento de culpa o incluso el miedo al abandono por parte de la pareja. Conclusión principal: El fenómeno de la infertili-dad continúa siendo un grave problema para miles de parejas que desean tener un hijo. Aunque esta estigmatización suele tener diferentes conse-cuencias dependiendo de diversos factores culturales, existen una serie de aspectos coincidentes sin importar el país del que se provenga.

Contaminantes en la alimentación infantil. Revisión bibliográfica

Objetivo principal: Actualizar el conocimiento actual existente sobre contaminantes en alimentos y productos elaborados específicamente para la población infantil. Metodología: Se realizó una revisión bibliográfica de los artículos disponibles publicados hasta marzo de 2019, en las siguientes bases de datos bibliográficas: PubMed, Scopus y Web of Science. Resultados principales: Son múltiples los contaminantes en los alimentos de consumo infantil, destacando entre ellos los metales pesados, micotoxinas, ftalatos, bisfenol A (BPA), contaminantes orgánicos persistentes (PCBs), contaminantes microbiológicos y metilmercurio, entre otros. Conclusión principal: Se necesitan datos adicionales que analicen la exposición y efec-tos del consumo de dichos contaminantes para la evaluación de riesgos y la distribución de las principales fuentes de contaminación.

Desafíos en la formación en promoción de la salud en estudiantes universitarios

La promoción de la salud es “considerada un proceso que busca fortalecer las habilidades y capacidades de las personas para emprender una acción”. Asimismo, busca potenciar el trabajo con los grupos o las comunidades para actuar de manera mancomunada con el fin de ejercer control sobre los determinantes de la salud [Fragmento de texto].

Enfrenté desafíos inesperados durante mi carrera profesional

El presente es el Relato Biográfico de una enfermera que trabajó de manera paralela en Control de Infecciones Intrahospitalarias (IIH), actual Infecciones Asociadas a la Atención en Salud (IAAS) y la atención de enfermos portadores de VIH. El objetivo del estudio fue conocer la vivencia de una profesional en el área de Control de Infecciones desde sus inicios hasta la actualidad. Se llevó a cabo un abordaje cualitativo descriptivo basado en una entrevista en profundidad para analizar esta experiencia de vida.  La informante aportó una reflexión crítica sobre su vivencia laboral y las implicancias a nivel personal y familiar. Su tránsito por este trabajo la ha posicionado como referente en el ámbito de Control de Infecciones. Reconoce que existen desafíos que han sido abordados de manera insuficiente y que son necesarios para mejorar la calidad de la atención de personas en ambas áreas.

The role of perceived organizational support for nurses' ability to handle and resolve ethical value conflicts: A mixed methods study

Abstract

Aim

To explore if and how nurses' perceived organizational support affects their ability to handle and resolve ethical value conflicts.

Design

A mixed methods design with a longitudinal questionnaire survey and focus group interviews.

Methods

A questionnaire survey in six hospitals in two Swedish regions provided data from 711 nurses responding twice (November–January 2019/2020 and November–January 2020/2021). A cross-lagged path model tested the mutual prospective influence between the organizational climate of perceived organizational support, frequency of ethical value conflicts, and resulting moral distress. Four focus group interviews were conducted with 21 strategically selected nurses (April–October 2021). Qualitative data collection and analysis were inspired by Grounded Theory.

Results

A climate of perceived organizational support was empowering, contributing to role security. It prospectively decreased the frequency of ethical value conflicts but not the moral distress when conflicts did occur.

Conclusion

It is important to facilitate the development of perceived organizational support among nurses, but also to reduce the occurrence of ethical value conflicts that the nurses cannot resolve.

Implications for the Profession

By ensuring a shared care ideology, good inter-professional relations within the entire care organization, providing clear and supportive organizational structures, and utilizing competence adequately, healthcare managers can facilitate and support the development of perceived organizational support among nurses. Nurses who are empowered by perceived organizational support are stimulated by and take pride in their work and experience the work as meaningful and joyful.

Impact

The study addressed the question of whether healthcare organizations could support nurses to resolving ethical value conflicts, and thus reduce moral distress. Perceived organizational support is related to factors such as ideological caring alignment and supportive organizational preconditions. This study contributes specific knowledge about how healthcare organizations can empower nurses to effectively resolve ethical value conflicts and thereby reduce their moral distress.

Patient or Public Contribution

No patient or public contribution.

Partnership‐based nursing practice framework for patients with advanced chronic obstructive pulmonary disease and their families—A discursive paper

Abstract

Aim

The increase in the number of people with chronic obstructive pulmonary disease (COPD) and the disease burden, has prompted concerted efforts to improve healthcare, particularly outpatient services. In line with these attempts the Partnership-Based Nursing Practice Theoretical Framework for People with COPD was developed to guide outpatient nursing care. The principal approach of the framework is a ‘Dialogue’ with the patients, which has four components: ‘Establishing family involvement’, ‘Assisting living with symptoms’ and ‘Facilitating access to healthcare’, with the primary goal being ‘Enhancement of the health experience’. With new knowledge, research on the framework, and extensive experience in using it, a need arose to modify the framework to maximize its clinical utility.

Design

Discursive paper.

Methods

A narrative review and critical reflection was conducted to revise the nursing practice framework via selected literature search from 2012 to 2022, research on the framework, and the authors' reflections on the clinical experience of using the framework.

Results

The nursing practice framework highlights capacities and possibilities that lie in the nurse–patient relationship. The overarching dialogue in the revised framework includes both patients and families. The action-related component ‘Assisting living with the disease’ was added to the framework to underscore the significance of attempting to understand what may lie ahead for patients and families. The other action-related components are as follows: ‘Assisting living with symptoms’ and ‘Facilitating access to healthcare’. The primary goal remains unchanged: enhancing the ‘Health experience’.

Conclusion

Using the revised nursing practice framework in outpatient care may help to enhance the lives of people with COPD and their families, particularly at advanced stages of the disease. It may have transferability to other groups of people living with progressive diseases dealing with complicated health problems, and to reduce the usage of costly healthcare resources such as hospital care.

Implications for the Profession and/or Patient Care

The partnership-based nursing practice framework assumes an extension of conventional specialized respiratory service and embraces a comprehensive account for that which may influence the patient's health problems. This guidance, which holistically attends to patient-family needs of living with complicated and progressive health predicaments, is fundamental. It contributes to strengthening the disciplinary focus of nursing, interdisciplinary collaboration, person-family-centred quality nursing care and inspires research initiatives. Critical reflections and updates on nursing practice frameworks, such as this revision, are essential to advance nursing and healthcare.

Patient or Public Contribution

There is no direct patient- or public contribution.

Relationship between Framingham Cardiovascular Risk Score and cognitive performance among ageing rural Indian participants: a cross-sectional analysis

Por: Mensegere · A. L. · Sundarakumar · J. S. · Diwakar · L. · Issac · T. G. · SANSCOG Study Team · Gangadhar · Rao · Rao · Sivakumar
Objective

The burden of cardiovascular risk factors is increasing in India, which, in turn, can adversely impact cognition. Our objective was to examine the effect of cardiovascular risk factors measured by Framingham Risk Score (FRS) on cognitive performance among a cohort of healthy, ageing individuals (n=3609) aged ≥45 years from rural India.

Design

A cross-sectional analysis.

Setting

A rural community setting in southern India.

Participants

Healthy, ageing, dementia-free participants, aged 45 years and above, belonging to the villages of Srinivaspura (a rural community located around 100 km from Bangalore, India), were recruited.

Primary outcome measures

Using a locally adapted, validated, computerised cognitive test battery, we assessed cognitive performance across multiple cognitive domains: attention, memory, language, executive functioning and visuospatial ability.

Results

The median (IQR) age of the sample was 57 (50.65) and 50.5% were women. Multiple linear regression analysis showed that participants with higher FRS performed poorly in attention (visual attention (β=–0.018, p=0.041)), executive functioning (categorical fluency (β=–0.064, p

Conclusion

Increased cardiovascular risk as evidenced by FRS was associated with poorer cognitive performance in all cognitive domains among dementia-free middle-aged and older rural Indians. It is imperative to design and implement appropriate interventions (pharmacological and lifestyle-based) for cardiovascular risk reduction and thereby, prevent or mitigate accelerated cognitive impairment in ageing individuals.

Burden, determinants, consequences and care of multimorbidity in rural and urbanising Telangana, India: protocol for a mixed-methods study within the APCAPS cohort

Por: Lieber · J. · Banjara · S. K. · Mallinson · P. A. C. · Mahajan · H. · Bhogadi · S. · Addanki · S. · Birk · N. · Song · W. · Shah · A. S. · Kurmi · O. · Iyer · G. · Kamalakannan · S. · Kishore Galla · R. · Sadanand · S. · Dasi · T. · Kulkarni · B. · Kinra · S.
Introduction

The epidemiological and demographic transitions are leading to a rising burden of multimorbidity (co-occurrence of two or more chronic conditions) worldwide. Evidence on the burden, determinants, consequences and care of multimorbidity in rural and urbanising India is limited, partly due to a lack of longitudinal and objectively measured data on chronic health conditions. We will conduct a mixed-methods study nested in the prospective Andhra Pradesh Children and Parents’ Study (APCAPS) cohort to develop a data resource for understanding the epidemiology of multimorbidity in rural and urbanising India and developing interventions to improve the prevention and care of multimorbidity.

Methods and analysis

We aim to recruit 2100 APCAPS cohort members aged 45+ who have clinical and lifestyle data collected during a previous cohort follow-up (2010–2012). We will screen for locally prevalent non-communicable, infectious and mental health conditions, alongside cognitive impairments, disabilities and frailty, using a combination of self-reported clinical diagnosis, symptom-based questionnaires, physical examinations and biochemical assays. We will conduct in-depth interviews with people with varying multimorbidity clusters, their informal carers and local healthcare providers. Deidentified data will be made available to external researchers.

Ethics and dissemination

The study has received approval from the ethics committees of the National Institute of Nutrition and Indian Institute of Public Health Hyderabad, India and the London School of Hygiene and Tropical Medicine, UK. Meta-data and data collection instruments will be published on the APCAPS website alongside details of existing APCAPS data and the data access process (www.lshtm.ac.uk/research/centres-projects-groups/apcaps).

Defining anthropometric thresholds (mid-arm circumference and calf circumference) in older adults residing in the community: a cross-sectional analysis using data from the population representative Longitudinal Aging Study in India (LASI DAD)

Por: Bhagwasia · M. · Rao · A. R. · Banerjee · J. · Bajpai · S. · Khobragade · P. Y. · Raman · A. V. · Talukdar · A. · Jain · A. · Rajguru · C. · Sankhe · L. · Goswami · D. · Shanthi · G. S. · Kumar · G. · Varghese · M. · Dhar · M. · Gupta · M. · Koul · P. A. · Mohanty · R. R. · Chakrabarti · S.
Objectives

To identify factors associated with malnutrition (undernutrition and overnutrition) and determine appropriate cut-off values for mid-arm circumference (MAC) and calf circumference (CC) among community-dwelling Indian older adults.

Design

Data from the first wave of harmonised diagnostic assessment of dementia for Longitudinal Ageing Study in India (LASI-DAD) were used. Various sociodemographic factors, comorbidities, geriatric syndromes, childhood financial and health status were included. Anthropometric measurements included body mass index (BMI), MAC and CC.

Setting

Nationally representative cohort study including 36 Indian states and union territories.

Participants

4096 older adults aged >60 years from LASI DAD.

Outcome measures

The outcome variable was BMI, categorised as low (2), normal (18.5–22.9 kg/m2) and high (>23 kg/m2). The cut-off values of MAC and CC were derived using ROC curve with BMI as the gold standard.

Results

902 (weighted percentage 20.55%) had low BMI, 1742 (44.25%) had high BMI. Undernutrition was associated with age, wealth-quintile and impaired cognition, while overnutrition was associated with higher education, urban living and comorbidities such as hypertension, diabetes and chronic heart disease. For CC, the optimal lower and upper cut-offs for males were 28.1 cm and >31.5 cm, respectively, while for females, the corresponding values were 26 cm and >29 cm. Similarly, the optimal lower and upper cut-offs for MAC in males were 23.9 cm and >26.9 cm, and for females, they were 22.5 cm and >25 cm.

Conclusion

Our study identifies a high BMI prevalence, especially among females, individuals with higher education, urban residents and those with comorbidities. We establish gender-specific MAC and CC cut-off values with significant implications for healthcare, policy and research. Tailored interventions can address undernutrition and overnutrition in older adults, enhancing standardised nutritional assessment and well-being.

Analysis of cardiovascular risk factors for the viability of cornea donors: a case-control study

Objective

The main objective of the study was to evaluate the influence of arterial hypertension, diabetes, dyslipidaemia, smoking, alcoholism and COPD (chronic obstructive pulmonary disease) on the viability of the extracted tissue as well as the donor.

Design

Observational case–control study.

Setting

Regional hospital in Northern Spain.

Participants

1517 corneas were registered.

Interventions

Patients’ medical history was reviewed after corneal donation and evaluation. Previous medical information (age, sex and cardiovascular risk factors (CVRFs)) and data related to the donor (type of donor), the corneal tissue and its evaluation, and the viability of the implant were collected.

Results

A total of 1517 corneas were registered and 81.5% of the donors presented at least one CVRF. In relation to the viability of the donor, it was observed that having suffered from COPD reduced the viability of the donor (no COPD: 93.8% vs COPD: 88%; OR=0.49; 95% CI: 0.28 to 0.84) while alcohol consumption increased it (drinker or ex-drinker: 95.8% vs non-drinker: 92.5%; OR=1.84; 95% CI: 1.01 to 3.33). Regarding tissue viability, decreased viability was observed in the presence of COPD (no COPD: 72.5% vs COPD: 64; OR=0.67; 95% CI: 0.47 to 0.96) and diabetes mellitus (no diabetes: 72.9% vs diabetes: 67.2%; OR=0.76; 95% CI: 0.58 to 0.99). As regards the viability of the implant, a total of 1039 corneas (68.9%) were suitable, observing decreased viability when suffering from COPD (no COPD: 69.8% vs COPD: 60.7%; OR=0.67; 95% CI: 0.47 to 0.94) and increased when having an active smoking habit (no habit: 65.3% vs habit: 74.1%; OR=1.52; 95% CI: 1.21 to 1.91).

Conclusions

Through this study, it can be concluded that in the absence of absolute exclusion criteria for donors, the assessment of how CVRF, alcoholism and COPD may affect the donor provides details about the quality of the tissue to be obtained.

Anakinra or tocilizumab in patients admitted to hospital with severe covid-19 at high risk of deterioration (IMMCoVA): A randomized, controlled, open-label trial

by Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Karolinska KI/K COVID-19 Treatment Working Group , Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

Background

Anakinra and tocilizumab are used for severe Covid-19, but only one previous randomized controlled trial (RCT) has studied both. We performed a multi-center RCT comparing anakinra or tocilizumab versus usual care (UC) for adults at high risk of deterioration.

Methods

The study was conducted June 2020 to March 2021. Eligibility required ≥ 5 liters/minute of Oxygen to maintain peripheral oxygen saturation at ≥ 93%, CRP > 70 mg/L, ferritin > 500 μg/L and at least two points where one point was awarded for lymphocytes 9/L; D-dimer ≥ 0.5 mg/L and; lactate dehydrogenase ≥ 8 microkatal/L. Patients were randomly assigned 1:1:1 to receive either a single dose of tocilizumab (8 mg/kg) or anakinra 100 mg IV QID for seven days or UC alone. The primary outcome was time to recovery.

Results

Recruitment was ended prematurely when tocilizumab became part of usual care. Out of a planned 195 patients, 77 had been randomized, 27 to UC, 28 to anakinra and 22 to tocilizumab. Median time to recovery was 15, 15 and 11 days. Rate ratio for recovery for UC vs anakinra was 0.91, 0.47 to 1.78, 95% [CI], p = 0.8 and for UC vs tocilizumab 1.13, 0.55 to 2.30; p = 0.7. There were non-significant trends favoring tocilizumab (and to limited degree anakinra) vs UC for some secondary outcomes. Safety profiles did not differ significantly.

Conclusion

Premature closure of trial precludes firm conclusions. Anakinra or tocilizumab did not significantly shorten time to clinical recovery compared to usual care. (IMMCoVA, NCT04412291, EudraCT: 2020–00174824).

Effects of transcranial direct current stimulation combined with Pilates-based exercises in the treatment of chronic low back pain in outpatient rehabilitation service in Brazil: double-blind randomised controlled trial protocol

Por: da Silva · A. A. C. · Gomes · S. R. A. · do Nascimento · R. M. · Fonseca · A. K. · Pegado · R. · Souza · C. G. · Macedo · L. d. B.
Introduction

Chronic low back pain may be associated with pathoanatomical, neurophysiological, physical, psychological and social factors; thus, treatments to reduce symptoms are important to improve the quality of life of this population. We aimed to evaluate the effects of transcranial direct current stimulation (tDCS) combined with Pilates-based exercises compared with sham stimulation on pain, quality of life and disability in patients with chronic non-specific low back pain.

Methods and analysis

This is a protocol for a double-blind randomised controlled trial with participants, outcome assessor and statistician blinded. We will include 36 individuals with a history of non-specific chronic low back pain for more than 12 weeks and minimum pain intensity of 3 points on the Numerical Pain Rating Scale. Individuals will be randomised into two groups: (1) active tDCS combined with Pilates-based exercises and (2) sham tDCS combined with Pilates-based exercises. Three weekly sessions of the protocol will be provided for 4 weeks, and individuals will be submitted to three assessments: the first (T0) will be performed before the intervention protocol, the second (T1) immediately after the intervention protocol and the third (T2) will be a follow-up 1 month after the end of the intervention. We will assess pain, disability, central sensitisation, quality of life, pressure pain threshold, global impression of change, adverse events and medication use. The Numerical Pain Rating Scale and the Roland-Morris Disability Questionnaire will be used at T1 to assess pain and disability, respectively, as primary outcome measures.

Ethics and dissemination

This trial was prospectively registered in ClinicalTrials.gov website and ethically approved by the Ethics and Research Committee of the Faculty of Health Sciences of Trairi (report number: 5.411.244) before data collection. We will publish the results in a peer-reviewed medical journal and on institution websites.

Trial registration number

ClinicalTrials.gov (NCT05467566).

Quantitative changes in the corneal endothelium and central corneal thickness during anterior chamber inflammation: A systematic review and meta-analysis

by Germán Mejía-Salgado, Paula Tatiana Muñoz-Vargas, Carlos Cifuentes-González, Gabriela Flórez-Esparza, Rebeca Paquentín-Jiménez, Miguel Ángel Castro-Monreal, Naomi Medina-Galindo, Gilma Norella Hernández-Herrera, Luz Elena Concha-del-Río, Alejandra de-la-Torre

Purpose

To establish the effects of anterior chamber inflammation (ACI) on the corneal endothelium parameters and central corneal thickness (CCT).

Methods

We conducted a comprehensive literature review using medical databases (PubMed, EMBASE, VHL, and medRxiv) on March 8, 2023, for studies that included patients with ACI who had undergone specular microscopy or pachymetry. Case series with >10 patients, cross-sectional, case-control, and cohort studies were included. The risk of bias was assessed using CLARITY tools and validated scales such as those by Hassan Murad et al. and Hoy et al. A narrative synthesis and a quantitative standardized mean difference meta-analysis, I2 heterogeneity assessment, and publication bias tests were conducted. The study was registered in PROSPERO (CRD42023420148) and approved by the Universidad del Rosario ethical committee (DVO005 2277- CV1712).

Results

Thirty-four studies, encompassing 1,388 eyes with ACI, were included. Compared with healthy controls, overall, ACI eyes show significant mean differences in endothelial parameters (endothelial cell density (ECD), coefficient of variation (CV), and hexagonality (HEX)) (P Conclusion

ACI leads to significant alterations in endothelial parameters and CCT. The primary contributors to these changes are increased IOP, uveitis duration, and intraocular surgeries. Further studies are needed to explore the impact of ACI etiology on the endothelium, potential biases in IOP measurements during acute ACI episodes, and the potential necessity for monitoring the endothelial parameters and CCT in patients with chronic ACI.

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