Measurement-based care (MBC), defined as the routine use of patient-reported outcome measures (PROMs) to monitor symptoms and inform collaborative treatment decisions, has demonstrated benefits in youth mental healthcare. However, evidence on how to implement MBC within specialised child and adolescent obsessive-compulsive disorder (OCD) services remains limited. Existing MBC implementation studies in paediatric mental health services have largely focused on community, school-based or general outpatient settings, leaving an important knowledge gap in specialised multidisciplinary tertiary care. This protocol aims to assess organisational readiness, guide implementation planning and evaluate early implementation outcomes of MBC within a specialised paediatric OCD programme in Calgary, Alberta.

This protocol describes a single-site, three-phase mixed-methods implementation study that includes organisational readiness assessment, theory-informed implementation planning and evaluation of early implementation outcomes of MBC within a specialised child and adolescent OCD programme. Phase 1 employs an explanatory sequential mixed-methods approach to assess organisational readiness and contextual determinants using the Readiness Thinking Tool, informed by the Consolidated Framework for Implementation Research (CFIR). Phase 2 focuses on developing and operationalising the implementation plan, guided by the Quality Implementation Framework, through stakeholder co-design, workflow integration, staff training and iterative refinement. The MBC model integrates five PROMs: two general mental health measures and three OCD-specific domains. Phase 3 employs a convergent mixed-methods formative evaluation to assess implementation outcomes, using the Reach, Effectiveness, Adoption, Implementation and Maintenance framework, while CFIR guides the assessment of contextual and organisational determinants. Data sources include clinician, youth and caregiver surveys and interviews, PROM completion and score data and implementation field notes. Quantitative data will be analysed descriptively, while qualitative data will be analysed using a CFIR-guided directed content analysis approach.

Ethics approval was obtained from the University of Calgary Conjoint Health Research Ethics Board. This study will generate implementation knowledge to inform the integration and sustainment of MBC within specialised paediatric mental health services. By linking readiness assessment, structured implementation planning and formative evaluation, it will produce a context-specific, practice-oriented implementation blueprint for MBC in paediatric OCD clinic. Findings will be disseminated via peer-reviewed publications, conference presentations, stakeholder workshops, clinic feedback sessions and policy-focused knowledge exchange activities.

Measurement-based care (MBC) is a framework supporting the systematic and repeated use of standardised outcome measures, including patient-reported outcome measures (PROMs), to improve communication between patients and healthcare providers. PROMs provide valuable insights into patients’ health status and treatment outcomes, particularly when effectively integrated into clinical workflows through electronic health record (EHR) systems. This integration is especially important in the management of chronic diseases, which require sustained and coordinated patient-centred care where significant gaps remain. Embedding PROMs within EHR systems may help scale MBC for chronic disease management by transforming patient-reported data into actionable information within clinical practice. The impact of this integration on clinical outcomes in patients with chronic illnesses remains unclear. The objective of this systematic review is to identify and summarise evidence of the impact of the collection and clinical integration of PROMs through the EHR on clinical care outcomes in chronically ill patients. The findings of this review will inform and guide the future implementation of PROMs in routine clinical care using EHRs.

The research team will search MEDLINE (OVID), Embase (OVID), CINAHL (EBSCO), APA PsycInfo (OVID), Cochrane Library (Wiley), Scopus (Elsevier) and Web of Science (Clarivate). Two pairs of reviewers will independently screen studies based on inclusion and exclusion criteria, with disagreements resolved by the third reviewer. Another two pairs of reviewers will extract data from the articles that will be synthesised narratively, summarised in tabular form and categorised according to the framework for individual-level clinical outcomes. The quality of the studies will be evaluated based on the Mixed Methods Appraisal Tool.

Ethics approval is not required as the proposed systematic review will synthesise data from published research. The results of this review will be disseminated through academic peer-reviewed journals and conference presentations.

CRD420261297619.

Stroke, one of the leading causes of death worldwide, leads to disability in most patients, posing a burden on society and families. Intensive rehabilitation in the early stages is the most effective method of minimising these disabilities. Home-based rehabilitation strategies have emerged as a promising alternative to conventional approaches, as highlighted during the coronavirus disease pandemic. Currently, no systematic reviews are available on the effects of home-based lower extremity rehabilitation systems in patients with stroke, or on the design specifications for their further development. Therefore, we present a protocol for a systematic review and meta-analysis to provide up-to-date evidence on this topic.

The study search for this review will be conducted in October 2026 across five electronic databases—MEDLINE, CENTRAL, EMBASE, Web of Science and CHINAL—and will be supplemented by Google searches and manual screening of the reference lists of the finally included studies. The search strategy has been developed using relevant keywords such as stroke, lower extremity rehabilitation, robotics and virtual reality, and study selection, data collection and risk of bias assessment will be performed independently by two authors; if these yield different results, final decisions will be made after discussion with the third author. The risk of bias in the existing literature will be evaluated using appropriate tools and methods in accordance with the Cochrane group guidelines (eg, RoB 2, Risk of Bias in Nonrandomised Studies of Interventions). Moreover, the level of evidence presented by this study will be evaluated using the Grading of Recommendations Assessment, Development, and Evaluation approach. If feasible, we will conduct a meta-analysis using the RevMan Web version; otherwise, a narrative review will be presented.

Since this study will be conducted without recruiting participants or using personal information, ethical approval and informed consent are not required (PROSPERO registration number: CRD 42024551398). Our proposed study will provide important evidence for policymakers, rehabilitation providers and system developers, and the results will be published in a journal and presented at conferences.

Gambling encompasses all activities that involve betting or wagering money. It is highly prevalent both in Canada and worldwide. While most individuals gamble without experiencing harm, some develop problem gambling, which is associated with serious psychological, relational and financial outcomes. Sexual and gender diversity (SGD) populations experience disproportionately high rates of mental health disorders, although little is known about their gambling trajectories. Knowledge in this regard is mainly based on cross-sectional studies, with no longitudinal evidence being available internationally. This gap in the literature restricts understanding of how problematic gambling emerges and evolves among SGD populations. It also limits the development of prevention and harm reduction strategies tailored to their realities.

This five-year longitudinal study will use a mixed-methods explanatory and sequential design in two phases. The first phase is a prospective cohort study. A self-report questionnaire will be administered online via a web panel to Canadian residents who are 18 years of age or older, self-identify as SGD and have gambled at least once in the previous 12 months (n=2500). This survey will be repeated annually over the course of three years to describe respondents’ gambling habits, model their trajectories and identify factors associated with problematic gambling. The second phase is a descriptive qualitative study. Semi-structured interviews will be conducted with respondents from phase 1 who present problematic gambling (n=40) to explore their experiences and lived realities.

This research project has been ethically and scientifically approved by the Research Ethics Committee and by the CIUSSS de l’Estrie—CHUS scientific evaluation committee on November 3, 2025 (reference number: 2026-6060 Trajectoires-JHA-LGBTQ). For all phases of the study, written or verbal consent will be obtained from each participant. A copy of the consent form and contact information will be sent to each participant.