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Chronic rhinosinusitis: a qualitative study of patient and clinician experiences of the MACRO randomised controlled trial of surgical versus medical management

Por: Vennik · J. · McDermott · C. · Williams · S. J. · Thomas · M. · Boardman · J. · Philpott · C. M. · Little · P. · Schilder · A. · Hopkins · C.
Objectives

To explore patient and clinician experiences of participation in the MACRO randomised controlled trial (RCT)—which found endoscopic sinus surgery (ESS) to be clinically effective whereas clarithromycin was no better than placebo for chronic rhinosinusitis (CRS)—and to identify barriers and facilitators to the implementation of the trial results.

Design

Qualitative study embedded within the multicentre MACRO RCT. Semistructured interviews with patients and clinicians were analysed using thematic analysis.

Setting

21 secondary and tertiary ear, nose and throat centres in England and Scotland participating in the MACRO RCT.

Participants

20 CRS patients (16 with nasal polyps, 4 without) were interviewed approximately 6 months after trial completion, and 17 clinical staff including principal investigators (PIs), associate PIs and research nurses.

Results

This study explored patients’ and clinicians’ experiences of the trial to identify barriers and facilitators to implementing the findings. Adopting the outcomes of the trial would involve recommending surgery to more patients with CRS. Yet patient and clinician interviews highlighted polarised views on ESS among patients, between those with positive experiences and expectations of ESS and those expressing fear of complications and hesitancy to receive surgery. During the trial, many participants randomised to surgery reported rapid improvement in symptoms, but with postoperative challenges for some patients including pain, unexpected symptoms and variations in recovery period. Priorities for implementation include providing patients with information about risks and support to make informed choices. Clinicians also reflected on the resource implications for offering ESS to more patients.

Conclusions

ESS is effective for CRS, but patient hesitancy and recovery concerns persist. Implementation requires clear communication, recognition and respect for individual preferences, tailored support for decision-making and post-surgical care to optimise acceptance and outcomes.

Trial registration number

ISRCTN36962030.

Suicide Risk and Protective Factors in Nursing Students in the United States

ABSTRACT

Aim

This study examined cultural, contextual and psychological risk and protective factors for suicide risk (i.e., suicide ideation, planning and attempting in the past year) in a cross-sectional sample of nursing students in the United States.

Design

A cross-sectional study design was employed.

Methods

Nursing students (n = 9871) were selected from the national 2020–2021 Healthy Minds Study (HMS). Students reported their demographics, suicidality and non-suicidal self-injurious behaviour (NSSIB). They also completed validated self-report measures of depression, belonging and flourishing.

Results

Logistic regressions revealed that racial minority nursing students were at risk for suicidal ideation and attempts, and sexual minority students were at risk for suicidal ideation. Nursing students with a history of mental illness severe enough to seek treatment and those who reported more NSSIB also evidenced greater odds of reporting all forms of suicide risk. Specifically, the odds of suicidal ideation and attempts were more than three times greater for nursing students who reported NSSIB. Additionally, positive elements of flourishing only marginally protected against suicidal ideation, and belonging was not associated with any form of suicide risk.

Conclusion

Findings highlight the high number of nursing students at risk for suicidality and highlight potential demographic and psychological targets for suicide interventions. Impact: Early intervention during nursing school could impact suicide risk throughout a nurse's educational and professional journey. Thus, nurse educators should consider implementing suicide and mental health interventions in their programmes.

Patient or Public Contribution

No direct patient or public contribution.

Community advisory boards to inform behavioural health research in primary care: protocol for a scoping review

Por: McDermott · K. A. · Vonderheide · C. C. · Cronin · A. E. · Vranceanu · A.-M. · Plys · E.
Introduction

Most patients receive behavioural healthcare (BH) in a primary care setting, yet much of the BH research was not developed to account for eventual implementation. Areas of research and intervention that are considered priorities to patients may be absent from our existing knowledge base. Engaging the community in the research process can facilitate translation and uptake. A key strategy for community engagement is to employ a Community Advisory Board (CAB). CABs can assist in a number of research processes, including guiding research questions to fit the priorities of the community and creating research materials that are tailored to the patient population and healthcare setting. There is variability in practices and reporting standards for CABs. The field would benefit from a summary of the state of the current literature on CAB utilisation for BH research in primary care. To fill this gap, we will conduct a scoping review to answer the question, ‘What is known about the use of CABs in behavioural health studies in primary care?’.

Methods and analysis

We will use the guidelines for scoping reviews outlined by Arksey and O’Malley: (1) identifying the research question; (2) identifying relevant studies; (3) study selection; (4) charting the data and (5) collating, summarising and reporting the results. Our reporting of the results will be guided by the Arnos and colleagues Toolkit for Project-Based Community Advisory Boards, a set of practical guidelines for employing a CAB. To this end, we will report on how well CABs currently employed in BH primary care research match existing guidelines and what gaps need to be filled by future research.

Ethics and dissemination

This review does not require ethics board approval, as no patient data will be collected. We will disseminate findings primarily through journal publications and conference presentations.

Trial registration number

This scoping review protocol was registered on the Open Science Framework (https://osf.io/pa3rz/?view_only=31c558eb395a4a9482ee9c5b57ca1c4c)

Socioeconomic and demographic predictors of extracurricular achievements among UK medical students (FAST study)

Por: Ferreira · T. · Collins · A. M. · Handscomb · A. · French · B. · Bolton · E. · Fortescue · A. · Plumb · E. · Feng · O. · The FAST Collaborative · Fallows · Valnarov-Boulter · Kuo · Sagdeo · McDermott · Luo · Wong · Fitzsimons-West · Ho · Hemayet · Sreekumar · Burley · Stavrinou · Lew
Objective

To investigate the relationship between demographic characteristics and extracurricular achievements among UK medical students.

Design

National, cross-sectional survey.

Setting

All 44 UK medical schools recognised by the General Medical Council.

Participants

8,395 medical students.

Outcomes

Binary indicators of extracurricular engagement, including PubMed-indexed authorship, academic presentations, quality improvement projects, leadership roles and academic prizes. Logistic regression models were used to explore associations with demographic and extracurricular achievement predictors.

Results

Logistic regression analysis showed that students from private schools (OR 1.35, CI 1.20 to 1.53, p

Conclusions

Significant disparities in extracurricular achievement exist among UK medical students, principally associated with gender, private schooling and familial links to medicine. Apparent ethnic differences were largely attenuated after adjustment for other variables, indicating socioeconomic factors as stronger predictors of engagement. Given the role of these achievements in postgraduate selection, targeted interventions by medical schools and professional bodies to widen access to funding, mentorship and structured guidance for all students, regardless of perceived advantage, may support equitable opportunity without undermining merit-based standards.

Specialty choices among UK medical students: certainty, confidence and key influences--a national survey (FAST Study)

Por: Ferreira · T. · Collins · A. M. · Handscomb · A. · French · B. · Bolton · E. · Fortescue · A. · Plumb · E. · Feng · O. · the FAST Collaborative · Fallows · Valnarov-Boulter · Kuo · Sagdeo · McDermott · Luo · Wong · Fitzsimons-West · Ho · Hemayet · Sreekumar · Burley · Stavrinou · Lew
Objective

To explore factors influencing UK medical students’ specialty choices and examine variations in these influences across demographic groups and stages of training.

Design

National, cross-sectional online survey.

Setting

All 44 UK medical schools recognised by the General Medical Council.

Participants

8,395 medical students.

Primary and secondary outcomes

The primary outcome was the specialty preferences of UK medical students. The secondary outcomes were factors behind these preferences and how these factors vary across demographic groups and different stages of training.

Results

General Practice (15.3%), Paediatrics (10.6%) and Anaesthetics (9.9%) were the most preferred specialties among final-year students. Work-life balance (84.1%), compatibility with family life (78.2%), positive training experiences (85.2%) and future specialty outlook (74.9%) were key factors influencing specialty choice. Only 23.1% of students felt confident about securing a specialty training post, with confidence higher among males (OR 1.36, 95% CI 1.21 to 1.52, p

Conclusions

This study highlights disparities in specialty preferences and influencing factors among UK medical students. A focus on improving career guidance, exposure to various specialties and supporting equitable access to training opportunities is essential for fostering a motivated and sustainable medical workforce.

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