Conectar
by Elizabeth Dufourcq Sekatcheff, Christian Godon, Aymeric Bailly, Loïc Quevarec, Virginie Camilleri, Simon Galas, Sandrine Frelon
Wildlife is subject to various sources of pollution, including ionizing radiation. Adverse effects can impact the survival, growth, or reproduction of organisms, later affecting population dynamics. In invertebrates, reproduction, which directly impacts population dynamics, has been found to be the most radiosensitive endpoint. Understanding the underlying molecular pathways inducing this reproduction decrease can help to comprehend species-specific differences in radiosensitivity. From our previous studies, we found that decrease in reproduction is life stage dependent in the roundworm Caenorhabditis elegans, possibly resulting from an accumulation of damages during germ cell development and gamete differentiation. To go further, we used the same experimental design to assess more precisely the molecular determinants of reproductive toxicity, primarily decreases in gamete number. As before, worms were chronically exposed to 50 mGy·h−1 external gamma ionizing radiation throughout different developmental periods (namely embryogenesis, gametogenesis, and full development). To enable cross species extrapolation, conserved molecular pathways across invertebrates and vertebrates were analysed: apoptosis and MAP kinase Ras/ERK (MPK-1), both involved in reproduction and stress responses. Our results showed that these pathways are life-stage dependent, resulting from an accumulation of damages upon chronic exposure to IR throughout the life development. The Ras/ERK pathway was activated in our conditions in the pachytene region of the gonad where it regulates cell fate including apoptosis, but not in the ovulation zone, where it controls oocyte maturation and ovulation. Additionally, assessment of germ cell proliferation via Ras/ERK pathway showed no effect. Finally, a functional analysis of apoptosis revealed that while the decrease of the ovulation rate is caused by DNA-damaged induced apoptosis, this process does not occur in spermatocytes. Thus, sperm decrease seems to be mediated via another mechanism, probably a decrease in germ cell proliferation speed that needs further investigation to better characterize sex-specific responses to IR exposure. These results are of main importance to describe radio-induced reprotoxic effects and contribute as weight of evidence for the AOP #396 “Deposition of ionizing energy leads to population decline via impaired meiosis”.To explore potential areas of low-value home-based nursing care practices, their prevalence and related influencing factors of nurses and nursing assistants working in home-based nursing care.
A quantitative, cross-sectional design.
An online survey with questions containing scaled frequencies on five-point Likert scales and open questions on possible related influencing factors of low-value nursing care. The data collection took place from February to April 2022. Descriptive statistics and linear regression were used to summarize and analyse the results.
A nationwide sample of 776 certified nursing assistants, registered nurses and nurse practitioners responded to the survey. The top five most delivered low-value care practices reported were: (1) ‘washing the client with water and soap by default’, (2) ‘application of zinc cream, powders or pastes when treating intertrigo’, (3) ‘washing the client from head to toe daily’, (4) ‘re-use of a urinary catheter bag after removal/disconnection’ and (5) ‘bladder irrigation to prevent clogging of urinary tract catheter’. The top five related influencing factors reported were: (1) ‘a (general) practitioner advices/prescribes it’, (2) ‘written in the client's care plan’, (3) ‘client asks for it’, (4) ‘wanting to offer the client something’ and (5) ‘it is always done like this in the team’. Higher educational levels and an age above 40 years were associated with a lower provision of low-value care.
According to registered nurses and certified nursing assistants, a number of low-value nursing practices occurred frequently in home-based nursing care and they experienced multiple factors that influence the provision of low-value care such as (lack of) clinical autonomy and handling clients' requests, preferences and demands. The results can be used to serve as a starting point for a multifaceted de-implementation strategy.
STROBE checklist for cross-sectional studies.
No Patient or Public Contribution.
Nursing care is increasingly shifting towards the home environment. Not all nursing care that is provided is effective or efficient and this type of care can therefore be considered of low-value. Reducing low-value care and increasing appropriate care will free up time, improve quality of care, work satisfaction, patient safety and contribute to a more sustainable healthcare system.
In older adults with type 2 diabetes (T2D), overtreatment with hypoglycaemic drugs (HDs: sulfonylureas, glinides and/or insulins) is frequent and associated with increased 1-year mortality. Deintensification of HD is thus a key issue, for which evidence is though limited. The primary objective of this study will be to estimate the effect of deintensifying HD on clinical outcomes (hospital admission or death) within 3 months in older adults (≥75 years) with T2D.
We will emulate with real-world data a target trial, within The Health Improvement Network cohort, a large-scale database of data collected from electronic medical records of 2000 general practitioners in France. From 1 January 2010 to 28 February 2019, we will include eligible patients ≥75 years who will have T2D, a stable dose of HDs, glycated haemoglobin A1c (HbA1c) value 75 mmol/mol within 1 year. Participants will be followed from baseline to 12 months after randomisation, administrative censoring, or death, whichever occurs first. A pooled logistic regression will be used to estimate the treatment effect on the incidence of the outcomes.
No ethical approval is needed for using retrospectively this fully anonymised database. The results will be disseminated during conferences and through publications in scientific journals.
The study aims to analyse the principal causes of patients' care calls and compare differences before and after inpatient beds' technological modernization in a surgical breast oncological ward.
A prospective observational study was conducted under the STROBE guidelines. Data were collected from June to September 2022.
Statistical analyses were performed to compare each reason for care calls, by shifts and pre and post-inpatient bed modernization.
Two thousand five hundred and fifty-nine care request calls were analysed during the 202 observed shifts. The most frequent reason was related to the requests for positions.
Technological modernization of the beds has not led to effective—positive—changes; on the contrary, it seems at first glance to show an upward trend in calls above all in the short period after the changes.
What problem did the study address? By analysing the principal causes of care calls and comparing the differences before and after inpatient beds' technological modernization, this study evaluates if inpatient gear or device modernization can impact care call requests. What were the main findings? The results show that the most frequent reasons for care calls were position, possession and other. These findings seem not superimposable; the hypothesis supported by the international literature in which the causes relating to potty and pain were found among the main reasons. Where and on whom will the research have an impact? These results could impact the care organizational area in nursing care and could improve care quality, patient satisfaction and safety.
This prospective observational study was conducted following STROBE guidelines.
After adequate information (presentation, design methods and objectives), all unit healthcare staff agreed to collaborate in the study.
To identify strategies that develop clinical nursing leadership competencies among staff nurses, and to explain the contextual elements and mechanisms that underpin the development of clinical nursing leadership competencies.
Realist review according to the Realist and Meta-narrative Evidence Syntheses—Evolving Standards (RAMESES).
PubMed, Embase, CINAHL, Web of Science, Wiley Online Library, PsycInfo and ProQuest were searched from January 2000 until October 2022.
Three iterative phases: (1) development of initial programme theory, (2) structured searches for relevant published and grey literature and (3) data synthesis and interpretation by researchers and theory triangulation, and discussions within the research group.
Multiple context–mechanism–outcome configurations were extracted from 10 reports that explain how, under what circumstances and why strategies can facilitate (or discourage) staff nurses to act as clinical leaders. Reports were both quantitative and qualitative in design, originating from English-speaking countries only.
A logic model was developed and suggests four contexts and five mechanisms underlying the development of clinical nursing leadership. Growth in clinical nursing leadership was mainly experienced through experiential learning, which was enhanced by a supportive relationship with a coach or mentor, the use of reflective practices and modelling from other leaders. Furthermore, a supportive work environment triggers ownership, confidence and motivation, and thereby growth in clinical nursing leadership competencies.
Fostering competencies for clinical leadership among staff nurses requires multifaceted strategies. Strategies are successful if, and only if, they combine learning by doing, by knowing and by observing, and establish a responsive work environment. Hospital policy should ensure that staff nurses have access to reciprocal relationships with role models or a coach. In order to grow as clinical nurse leader, ownership and self-reflection on own leadership behaviour need to be facilitated.
Prospero ID CRD42021292290.
To explore patient experiences of intimacy and sexuality in those living with inflammatory bowel disease.
An interpretative phenomenological study guided by van Manen's framework. Thematic analysis was conducted through interpretation and reflection on four existential domains: body, relationships, time and space.
Data were collected during 2019–2021 from 43 participants via face-to-face or telephone interviews, as well as anonymous collection of narratives submitted via Google Forms.
Four themes were identified: Sexuality as lived incompleteness was the overarching theme representing the essence of the experiences of intimacy and sexuality. This theme covered the four main themes: Otherness of the body, Interrupted connectedness, Missing out on life fullness and Fragmented openness and each corresponded to an existential domain. Intimacy and sexuality are negatively affected by inflammatory bowel disease, with impact on quality of life. Patients experienced grieving multiple losses, from body image and control, to choice of partners and future opportunities. The four domains were difficult to separate and a close inter-relationship between each domain was acknowledged.
A model was developed to draw new theoretical insights to understanding the relationship between sexual well-being and psycho-emotional distress similar to grief.
First qualitative study to explore intimacy and sexuality experiences of those living with inflammatory bowel disease. Illness impact on sexuality has negative psycho-emotional implications as a result of losing the old self and capacity to have the desired relationships/sex life. A theoretical model was developed in an attempt to illustrate the close relationship of intimacy, sexuality and psycho-emotional well-being.
Patients were involved in the study design.
by Bryan McCann, Simon C. Hunter, Kareena McAloney-Kocaman, Paul McCarthy, Jan Smith, Eileen Calveley
The coronavirus (COVID-19) pandemic had wide-ranging negative impacts on mental health. The pandemic also placed extraordinary strain on frontline workers who were required to continue working and putting themselves at risk to provide essential services at a time when their normal support mechanisms may not have been available. This paper presents an evaluation of the Time for You service, a rapidly developed and implemented intervention aimed at providing frontline workers with quick access to flexible online mental health support. Time for You provided service users with three service options: self-guided online cognitive behavioural therapy (CBT) resources; guided engagement with online CBT resources; 1–1 psychological therapy with trainee sport and exercise psychologists and trainee health psychologists. A process evaluation informed by the Consolidated Framework for Implementation Research considered service fidelity, adaptations, perceived impact, reach, barriers, and facilitators. Interviews with project managers (n = 5), delivery staff (n = 10), and service users (n = 14) explored perceptions of the service implementation and outcomes, supported by data regarding engagement with the online CBT platform (n = 217). Findings indicated that service users valued the flexibility of the service and the speed with which they were able to access support. The support offered by Trainee Psychologists was perceived to be of high quality, and the service was perceived by service users to have improved mental health and wellbeing. The rapid implementation contributed to issues regarding appropriate service user screening that led to trainee psychologists being unable to provide the service users with the support they needed as the presenting issues were outside of trainees’ competencies. Overall, the findings suggest that interventions offering flexible, online psychological support to frontline workers can be an effective model for future interventions. Trainee psychologists are also able to play an important role in delivering such services when clear screening processes are in place.Objetivo: Evaluar la efectividad de un instrumento interdisciplinario, desarrollado y aplicado en una unidad de cuidados intensivos de adultos para reducir las infecciones asociadas a la atención de la salud. Metodología: Estudio transversal, cuantitativo, realizado de enero de 2018 y junio de 2019, en una UCI de un Hospital de Paraná-Brasil. Resultados: Se evaluaron 759 pacientes. Antes de la aplicación del instrumento, las medias eran respectivamente: 1,00 para IRAS CVC; 6.78 ID IPCS; 3,22 VAP; 21,62 DIPAV y 0,88 para IRAS CVD, después con la aplicación del Fast Checklist: 0,11 para IRAS CVC (p = 0,11); 0,86 ID IPCS (p = 0,017); 0,33 VAP (p = 0,001); 2,83 DIPAV (p = 0,003) y 0,00 para IRAS ECV (p = 0,0002). Conclusión principal: El estudio demostró que la implementación y aplicación diaria de la Lista de Verificación Rápida fue efectiva para la reducción de las IRAS en la Unidad de Cuidados Intensivos.
International evidence shows that nurses' work environments affect patient outcomes, including their care experiences. In Chile, several factors negatively affect the work environment, but they have not been addressed in prior research. The aim of this study was to measure the quality of the nurse work environment in Chilean hospitals and its association with patient experience.
A cross-sectional study of 40 adult general high-complexity hospitals across Chile.
Participants included bedside nurses (n = 1632) and patients (n = 2017) in medical or surgical wards, who responded to a survey. The work environment was measured through the Practice Environment Scale of the Nursing Work Index. Hospitals were categorized as having a good or poor work environment. A set of patient experience outcomes were measured through the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey. Adjusted logistic regression models were used to test associations between the environment and patient experiences.
For all outcomes, the percentage of patients satisfied was higher in hospitals with good as compared to poor work environments. In good environment hospitals patients had significantly higher odds of being satisfied with communication with nurses (OR 1.46, 95% CI: 1.10–1.94, p = 0.010), with pain control (OR 1.52, 95% CI: 1.14–2.02, p = 0.004), and with nurses' timely responses in helping them to go to the bathroom (OR 2.17, 95% CI: 1.49–3.16, p < 0.0001).
Hospitals with good environments outperform hospitals with poor environments in most patient care experience indicators. Efforts to improve nurses' work environment hold promise for improving patient experiences in Chilean hospitals.
Hospital administrators and nurse managers should value, especially in the context of financial constraints and understaffing, the implementation of strategies to improve the quality of nurses´ work environments so that they can provide patients with a better care experience.
Introducción: Actualmente, el uso de tecnologías innovadoras ha ayudado a los profesionales a gestionar mejor el volumen de información de manera inteligente, para facilitar y optimizar el uso de acciones y prácticas preventivas. Entendido como un recurso capaz de expandir o acceder a datos, nuestro objetivo es analizar el tema del suicidio en Rio Grande do Sul, en el período de 2010 a 2019, desde el portal municipal de Business Intelligence. Método: Una investigación es de naturaleza cuantitativa, de tipo descriptivo, basada en los registros de muertes por suicidio en el estado de Rio Grande do Sul, escuchada por el portal público de inteligencia empresarial (BI). Los datos fueron analizados, basados en el número bruto de muertes por suicidio en la macro-región del Sur, registrada en el Portal BI / DGTI. Se realizó una descripción del número de muertes según el año, el sexo, el grupo de edad y la tasa de suicidios. Resultados: un total de 11,774 muertes por suicidio, registradas en los últimos 10 años, o el número más alto que ocurrió en los años 2017 y 2019, entre los hombres, con tasas más altas en los grupos de edad entre 20 y 69 años. Una tasa más alta registrada fue en 2019, con 12.41 muertes por cada 100,000 habitantes. Concluimos con este estudio sobre el uso de Bussiness Intelligence, que permite acciones más efectivas en la prevención del suicidio.
Objetivo principal: relatar a experiência das práticas de educação em saúde, por um grupo de profissionais, integrantes da Atenção Primária em Saúde, em zonas de prostituição de Rio Grande/RS. Metodologia: Trata-se de um relato de experiência, realizado em 2016, por um grupo de profissionais (Enfermeira, Assistente Social, Educador Social e motorista), vinculados a secretaria de saúde de um município do extremo sul do Brasil. Em uma unidade móvel de saúde, o grupo percorreu as zonas de prostituição (postos de gasolina, ruas e boates). De abril a agosto de 2016, os profissionais de saúde desenvolveram ações de conscientização sobre a importância dos riscos inerentes a profissão, sobre o cuidado de si, através da oferta de testes rápidos, distribuição de preservativos masculinos e femininos e lubrificantes íntimos. Resultados: Vinte zonas de prostituição foram encontradas pela equipe, concentrados em ruas, boates e postos de combustíveis espalhados pela cidade. Cerca de 200 profis-sionais do sexo, foram atendidas pelo grupo, sendo ofertados mensalmente 40 exames de testes rápidos e 40 carteiras sociais. Quanto a pre-venção as ISTs, foram distribuídos 1500 preservativos masculinos, 200 preservativos femininos e 500 lubrificantes íntimos. Conclusão: A equipe, de forma itinerante, atuou de forma exitosa na busca, não somente de orientá-las quanto aos riscos inerentes a profissão, mas também de conhecer um pouco da sua história, do resgate a cidadania e da autoestima, a uma população que tem seus direitos frequentemente violados. Percebe-se nessa vivência a importância da educação em saúde como um instrumento de promoção e prevenção, na busca pela valorização dessas pessoas.
Objetivo principal: El presente artículo tiene como objetivo determinar el grado de cumplimiento de los cinco momentos para la higiene de manos de la OMS del personal sanitario de diferentes servicios/unidades de un Hospital General Universitario de la Región de Murcia. Metodología: Estudio observacional descriptivo transversal. De forma aleatoria y durante un periodo continuado se procedió a registrar el grado de cumplimentación de los cinco momentos de la higiene de manos. Se recogieron variables asociadas al momento de realización de la higiene de manos: profesional que la realiza, área/servicio asistencial, uso de guantes y consumo de solución hidroalcohólica. Resultados principales: Participaron 137 profesionales (41 de medicina, 66 de Enfermería y 30 auxiliares de Enfermería). El cumplimiento global de las indicaciones de los cinco momentos ha sido del 42,02%. Este resultado varía en función de las variables uso de guantes, profesional que realiza la higiene de manos y área o servicio donde la realiza. Los profesionales de Enfermería son los que alcanzan un mayor porcentaje de cumplimiento. Conclusión principal: El grado de cumplimien-to de los cinco momentos para la higiene de manos de la OMS en el Hospital General Universitario estudiado está muy por debajo del valor ideal. Es necesario implementar medidas de intervención educativa que mejoren el cumplimiento de la técnica para aumentar la calidad asistencial y la seguridad del paciente.
Objetivo principal: mapear la producción del conocimiento acerca de la temática violencia contra niños y adolescentes de una Institución Federal de Educación Superior (IFES) del Sur do Brasil. Metodología: Se trata de una investigación documental, a través de mapeo de la producción discente y docente de los cursos de graduación del área de la salud, educación, derecho, entre 1990 y 2016 en diferentes bases disponibles de la Universidad. Resultados: se constituyeron la muestra de la investigación, 86 producciones académicas, siendo 47 trabajos de conclusión de curso, 10 pro-yectos de investigación y 29 artículos científicos sobre violencia. Las producciones presentaron un crecimiento a partir de 2006, con un aumento considerable en 2012 y la Enfermería fue responsable del 46,5% de toda la producción académica y la atención a niños y adolescentes víctimas de violencia fue el tema con el mayor número de producción. Conclusión: la importancia de abordar el tema en los currículos a fin de que todas las áreas del conocimiento puedan ejercer su coparticipación en la garantía de derechos de niños y adolescentes que son acometidas por la violencia.
FreshRSS 