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Salt intake across the hypertension care cascade in the Bangladeshi adult population: a nationally representative cross-sectional study

Por: Monower · M. M. · Abid · S. U. A. · Abrar · A. K. · Choudhury · S. R.
Objectives

This study aimed to examine the distribution of daily salt intake across the hypertension care cascade and assess the proportional distribution of these care cascade categories across various salt consumption level.

Design

A population-based national cross-sectional study.

Settings

Data from the Bangladesh STEPS 2018 survey were used, encompassing both urban and rural strata within all eight divisions. National estimates were generated from weighted data.

Participants

A diverse population of 6754 men and women aged 18–69 years was included in the study.

Outcome measures

Daily salt consumption was estimated using the spot urine sodium concentration following Tanaka equation. Distribution of salt intake among different categories of hypertension care cascade, including hypertensives, aware of hypertension status, on treatment and under control, was assessed.

Results

Individuals with hypertension consume more salt on average (9.18 g/day, 95% CI 9.02 to 9.33) than those without hypertension (8.95 g/day, 95% CI 8.84 to 9.05) (p

Conclusions

Individuals with hypertension consume significantly more salt than those without, with no significant variations in salt intake based on aware, treated and controlled hypertension. Adhering to WHO salt intake guidelines aids better blood pressure management. By addressing salt consumption across hypertension care cascade, substantial progress can be made in better blood pressure control.

Investigating the potential of aggregated mobility indices for inferring public transport ridership changes

by Maximiliano Lizana, Charisma Choudhury, David Watling

Aggregated mobility indices (AMIs) derived from information and communications technologies have recently emerged as a new data source for transport planners, with particular value during periods of major disturbances or when other sources of mobility data are scarce. Particularly, indices estimated on the aggregate user concentration in public transport (PT) hubs based on GPS of smartphones, or the number of PT navigation queries in smartphone applications have been used as proxies for the temporal changes in PT aggregate demand levels. Despite the popularity of these indices, it remains largely untested whether they can provide a reasonable characterisation of actual PT ridership changes. This study aims to address this research gap by investigating the reliability of using AMIs for inferring PT ridership changes by offering the first rigorous benchmarking between them and ridership data derived from smart card validations and tickets. For the comparison, we use monthly and daily ridership data from 12 cities worldwide and two AMIs shared globally by Google and Apple during periods of major change in 2020–22. We also explore the complementary role of AMIs on traditional ridership data. The comparative analysis revealed that the index based on human mobility (Google) exhibited a notable alignment with the trends reported by ridership data and performed better than the one based on PT queries (Apple). Our results differ from previous studies by showing that AMIs performed considerably better for similar periods. This finding highlights the huge relevance of dealing with methodological differences in datasets before comparing. Moreover, we demonstrated that AMIs can also complement data from smart card records when ticketing is missing or of doubtful quality. The outcomes of this study are particularly relevant for cities of developing countries, which usually have limited data to analyse their PT ridership, and AMIs may offer an attractive alternative.

Autologous blood products: Leucocyte and Platelets Rich Fibrin (L-PRF) and Platelets Rich Plasma (PRP) gel to promote cutaneous ulcer healing - a systematic review

Por: Napit · I. B. · Shrestha · D. · Neupane · K. · Adhikari · A. · Dhital · R. · Koirala · R. · Gopali · L. · Ilozumba · O. · Gill · P. · Watson · S. I. · Choudhury · S. · Lilford · R. J.
Objective

To summarise evidence on the effectiveness of Platelet-Rich Plasma (PRP) gel and Leucocyte and Platelet Rich Fibrin (L-PRF) gel as agents promoting ulcer healing compared with the standard wound dressing techniques alone.

Design

Systematic review.

Eligibility criteria

Individual patient randomised controlled trials on skin ulcers of all types excluding traumatic lesions.

Intervention group: treatment with topical application of L-PRF gel or PRP gel to the wound surface.

Control group: treatment with standard skin ulcer care using normal saline, normgel or hydrogel dressings.

Information sources

Medline (Ovid), Excerpta Medica Database (EMBASE), Scopus, Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Web of Science and manual search of studies from previous systematic reviews and meta-analyses. The papers published from 1946 to 2022 with no restriction on geography and language were included. The last date of the search was performed on 29 August 2022.

Data extraction and synthesis

Independent reviewers identified eligible studies, extracted data, assessed risk of bias using V.2 of the Cochrane risk-of-bias tool for randomised trials tool and assessed certainty of evidence by using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach.

Main outcome measures

Time to complete healing, proportion healed at a given time and rate of healing.

Results

Seven studies met the inclusion criteria, five using PRP gel and two using L-PRF gel. One study showed a better proportion of complete healing, three reported reduced meantime to complete healing and five showed improved rate of healing per unit of time in the intervention group. The risk of bias was high across all studies with one exception and the GRADE showed very low certainty of evidence.

Conclusion

The findings show potential for better outcomes in the intervention; however, the evidence remains inconclusive highlighting a large research gap in ulcer treatment and warrant better-designed clinical trials.

PROSPERO registration number

CRD42022352418.

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