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Stress and Health‐Related Quality of Life in Adults With Type 1 Diabetes: The Mediating Role of Perceived Support and Treatment Adherence

ABSTRACT

Aims

To examine the associations among diabetes-related stress, treatment adherence, perceived social support, and health-related quality of life (HRQoL) in adults with type 1 diabetes mellitus (DM1), and to explore the mediating roles of support and adherence in this relationship.

Design

A cross-sectional observational study using self-report standardised measures and mediation analysis.

Methods

A total of 772 Spanish adults with DM1 completed validated instruments measuring diabetes-related distress, perceived social support, treatment adherence, and HRQoL. Hierarchical multiple regression and serial mediation analysis (PROCESS Model 6, 10,000 bootstraps) were conducted, controlling for age, sex, and time since diagnosis.

Data Sources

Not applicable (primary data collection, not a review).

Results

Diabetes-related stress was the strongest predictor of lower HRQoL. Perceived social support and treatment adherence also contributed significantly. Mediation analyses indicated that the impact of stress on HRQoL was partially mediated by perceived social support and, in sequence, by treatment adherence. The indirect path through social support alone and the sequential path involving both mediators were significant.

Conclusion

Stress and social support are critical in understanding and improving HRQoL in adults with DM1. Treatment adherence appears to be influenced by perceived support, highlighting an indirect mechanism linking stress to quality of life.

Implications for the Profession and/or Patient Care

Healthcare professionals should integrate psychosocial assessments and interventions into routine diabetes care. Targeting stress reduction and enhancing social support may improve adherence and overall well-being in adults with DM1.

Impact

What problem did the study address? The study addressed the need to understand how psychosocial factors—specifically stress, perceived social support, and treatment adherence—contribute to HRQoL in adults with DM1. While prior research often focused on paediatric or clinical populations and rarely explored mediation models, this study sought to fill those gaps with data from a large community sample of adults.

What were the main findings? The main findings indicate that diabetes-related stress is the most significant predictor of reduced HRQoL. This relationship is partially mediated by perceived social support and, sequentially, by treatment adherence. While stress directly affects HRQoL, its negative impact is also channelled through diminished social support and decreased adherence. The indirect effect through treatment adherence alone was not significant.

Where and on whom will the research have an impact? The research has implications for adults living with DM1, particularly those in community settings outside of clinical supervision. It informs healthcare providers, diabetes educators, and policymakers on the importance of addressing emotional distress and strengthening support networks to improve both treatment adherence and overall quality of life.

Reporting Method

This study adhered to the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines for cross-sectional studies. All methods and results are reported in alignment with EQUATOR Network recommendations for transparent and rigorous research reporting.

Patient or Public Contribution

The study was conducted in collaboration with the Spanish Diabetes Federation (FEDE), which supported participant recruitment and dissemination through its affiliated associations. Patient input was incorporated throughout the study. A person with lived experience of type 1 diabetes contributed to the conceptual development of the research questions and the interpretation of findings. Their perspective helped ensure that the study design, choice of measures, and implications were relevant and meaningful to people living with the condition. This involvement supported a patient-centred approach to both the research and the manuscript preparation. Patients' participation as voluntary contributors was essential to the data collection process.

Global mapping of oral health plans, programmes and policies in countries with universal health coverage: a scoping review protocol

Introduction

This review aims to map oral health plans, programmes and policies worldwide in countries with universal health coverage.

Methods and analysis

This protocol describes a scoping review that will follow the Joanna Briggs Institute methodology and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Scoping Review checklist, guided by the PCC framework: Population—countries with universal health coverage (78 globally recognised); Concept—oral health plans, programmes and policies; Context—integration into health systems. Searches will be conducted in MEDLINE (PubMed), Scopus, Web of Science, Embase, Health System Evidence and Epistemonikos, with no restrictions on date, language or study type. Grey literature will be accessed through Google Scholar, OpenThesis and the Brazilian Digital Library of Theses and Dissertations. Official documents from ministries of health and international bodies, including the WHO and the International Monetary Fund, will also be reviewed. Two independent reviewers will screen titles and abstracts; a third will resolve disagreements. Eligible records will undergo full-text review. Data will be extracted into predefined categories reflecting health system components: population, structure, services, governance and oral health indicators. Results will be presented using tables, charts and figures to illustrate strategies and innovations.

Ethics and dissemination

This review does not involve primary data collection and does not require ethical approval. Results will be disseminated through a peer-reviewed publication and presentations at academic conferences and scientific events.

Study registration

Open Science Framework (DOI 10.17605/OSF.IO/RCP8N).

Asociación entre factores motivacionales y desempeño laboral de profesional enfermero en dos hospitales de tercer y cuarto nivel de complejidad

Introducción: La motivación cumple un rol fundamental sobre todo en el desempeño laboral del profesional de Enfermería. Esta motivación representa un factor protector tanto para el profesional de Enfermería como también al paciente que se encuentra a su cuidado. Se objetivó analizar la relación existente entre factores motivacionales y desempeño laboral del profesional de Enfermería quienes ejercen funciones en dos hospitales del departamento Central 2023. Metodología. Estudio observacional descriptivo transversal realizado en dos centros asistenciales de referencia nacional, de alta complejidad de la República del Paraguay, muestreo no probabilístico por conveniencia. El instrumento, un cuestionario pre-elaborado y validado. Resultados. Respeto al desempeño laboral, predominó el nivel alto. En referencia a las dimensiones del desempeño laboral, ha predominado mayoritariamente el nivel alto, no registrándose ningún participante en el nivel bajo. Al relacionar los factores motivacionales con el desempeño laboral, se encontró asociación estadísticamente significativa, con lo que se acepta la hipótesis de investigación que indica que existe asociación entre factores motivacionales y el desempeño laboral de profesionales de enfermería. Discusión. Al relacionar los factores motivacionales con el desempeño laboral, se observó una asociación estadísticamente significativa. Esto se respalda en un estudio realizado en Perú, cuyos resultados sugieren que el desempeño laboral de los profesionales de enfermería estaría influenciado por la dependencia de factores motivacionales extrínsecos. Conclusión: Se recomienda fortalecer programas de reconocimiento y mejora de condiciones laborales para estimular la motivación extrínseca, como implementar oportunidades de desarrollo profesional y participación en la toma de decisiones.

ABSTRACT

Introduction: Motivation plays a fundamental role, especially in the work performance of nursing professionals. This motivation represents a protective factor for both the nursing professional and the patient under their care. The objective was to analyze the existing relationship between motivational factors and work performance of nursing professionals who work in two hospitals in the Central department 2023. Methodology. A cross-sectional, descriptive, observational study carried out in two national reference, highly complex healthcare centers in the Republic of Paraguay, using a non-probabilistic convenience sampling. The instrument was a pre-prepared and validated questionnaire. Results. Regarding work performance, a high level predominated. Regarding the dimensions of work performance, the high level predominated, with no participants registered at the low level. When relating motivational factors with work performance, a statistically significant association was found, thereby accepting the research hypothesis that indicates an association between motivational factors and the work performance of nursing professionals. Discussion. When relating motivational factors to job performance, a statistically significant association was observed. This is supported by a study conducted in Peru, whose results suggest that nursing professionals' job performance may be influenced by their dependence on extrinsic motivational factors. Conclusion. Strengthen recognition programs and improve working conditions is recommended to stimulate extrinsic motivation, such as implementing opportunities for professional development and participation in decision-making.

Puff and psychosis: a retrospective cohort analysis of psychiatric hospitalisations in patients with schizophrenia and nicotine use

Por: Lay · S. · Nguyen · L. L. · Yan · Y. · Chan-Golston · A. M. · De Santiago · A. · Sidhu · R. · Yasaei · R.
Objectives

The association between smoking and patients with schizophrenia has been established through epidemiological studies on various populations. This behaviour not only increases the risk of medical comorbidities associated with smoking, but it can also interfere with treatment and ultimately worsen prognosis. This study aims to determine if nicotine use affects the cumulative number of psychiatric hospitalisations in patients with schizophrenia.

Design

This is a retrospective cohort study using 2018–2023 electronic medical record data.

Setting

Data was collected at an inpatient psychiatric hospital in Central California.

Participants

There were a total of 825 patients with diagnoses of schizophrenia or schizoaffective disorder who were admitted to the mental health hospital between 2018 and 2023.

Primary and secondary outcome measures

The primary outcome of interest was the number of psychiatric hospitalisations observed among the patients who were smokers versus those who were non-smokers. Our secondary objective was to determine the prevalence of certain medical comorbidities between these two groups.

Results

60.7% of patients had a lifetime smoking history. Accounting for matching, patients who smoked had significantly (p

Conclusions

Patients with schizophrenia and a lifetime smoking history had significantly more hospitalisations compared with patients with schizophrenia who were non-smokers. This can inform disease course in vulnerable populations with a greater propensity to self-medicate with substances. However, further research should be conducted to investigate other factors that can affect this relationship.

Experiencias de madres con accidentes domésticos infantiles: consideraciones a la luz del Modelo de Adaptación de Roy

Objetivo principal: Describir las experiencias de las madres que vivieron accidentes domésticos que involucraron a sus hijos, a la luz del Modelo de Adaptación de Roy.  Método: Estudio cualitativo. Los datos fueron recolectados a través de entrevistas y sometidos a la técnica de análisis de contenido. Se utilizó como marco teórico el Modelo de Adaptación de Roy. Resultados principales: Participaron 17 madres, cuyos discursos fueron agrupados en tres categorías: enfrentar el desafío de salvar la vida de su hijo; reconocer el momento de (falta de) cuidado de su hijo; y aprender de sus errores. Conclusión principal: Se identificaron madres con dificultades para reconocer sus errores y posibles negligencias, que les atribuyeron la responsabilidad del accidente al hijo. Los enfermeros, cuando basan su práctica clínica en el Modelo de Adaptación de Roy, deben prestarles atención a las necesidades emocionales de los sistemas adaptativos de los involucrados.

Tratamiento inmediato del neumotórax abierto: sellos torácicos ventilados vs. no ventilados. Una revisión sistemática

Objetivo principal: valorar la efectividad de los diferentes sellos torácicos existentes e identificar el tratamiento inmediato óptimo del neumotórax abierto. Metodología: revisión sistemática en bases de datos bibliográficas de gran repercusión en la comunidad científica, identificando estu- dios que analizaran la eficacia de los diferentes sellos torácicos. Resultados principales: los sellos torácicos comercializados no ventilados propician el desarrollo de un neumotórax a tensión, mientras que los ventilados evitan esta complicación. Esto es posible gracias a su función ventiladora y adhesiva, siendo el sello Russel® el que obtuvo mejores resultados. Conclusión principal: los sellos torácicos comercializados con canales ventilados laminados son los recomendados para el tratamiento del neumotórax abierto por evitar el desarrollo de un neumotórax a tensión, quedando en último lugar el uso de un sello completamente oclusivo.

Paciente con Síndrome Dolor Regional Complejo Tipo I

Paciente varón, de 32 años de edad, que consulta por dolor en muñeca derecha. Tras meses en rehabilitación, se diagnostica “epicondilitis” y se indica tratamiento quirúrgico, se retira yeso a las 6 semanas, se observa color azulado de toda la piel del antebrazo y mano, con hiperhidrosis y mucho vello. Ante la sospecha, se solicita gammagrafía con Tc99 que confirma el diagnóstico de “Síndrome de Dolor Regional Complejo tipo I simpático dependiente en grado II-III”. Derivado a la Unidad del Dolor donde es sometido a múltiples tratamientos, se implantan electrodos corticales a nivel de duramadre en la Cisura de Rolando. Tras no obtener resultados y observarse fibrosis a nivel del cuello, se retiran los electrodos. Posteriormente, recibe tratamiento fisioterapeutico-osteópatico mejorando ostensiblemente. Al cabo de 3 meses, vuelve a hacer vida normal, reincorporándose a su puesto de trabajo habitual perdido hace 9 años.

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