Conectar
by Maria Sabastin Sagayam, Priya Gupta, Ram Ramesh, Angan Sengupta
BackgroundThe Indian healthcare system continues to remain unstructured leading to sub-optimal health outcomes, not just in rural but even in urban areas. While physicians play a crucial role in shaping treatment trajectories and managing the referral process, their perspective on the referral system has received very limited academic attention in India. This study attempts to understand the archetypical physician’s referral mechanism and the factors influencing their referral practices. This study also highlights the challenges and possible solutions in operationalising an efficient referral process as suggested by the professionals.
MethodsIn-depth qualitative interviews were conducted with sixty-two physicians consisting of both general physicians and specialists from 19 different disciplines, associated with public and private hospitals in Bengaluru, India. The data, thus collected, was subjected to thematic analysis to generate relevant themes.
ResultsFive themes emerged from the thematic analysis from a phenomenological perspective based on the physicians’ lived experience. First of all, specialist physicians’ availability, accessibility, experience, and reputation strongly influenced referral recommendations. It was also observed that due to lack of a comprehensive healthcare provider database, personal connections and professional networks are utilised. Moreover, although physicians prioritize patients’ affordability and accessibility factors, referral counselling and caregiver-patient communication remained inadequate and required formalization. While the fourth theme clusters around several barriers related to communication, system inefficiencies, lack of awareness, accessibility and affordability among patients; the final theme suggests that the physicians emphasized on urgent need for clear guidelines, regulations and policies to streamline and monitor the referral system.
ConclusionThis research highlights that physicians recognize the systemic gaps leading to unsolicited health outcomes; yet they are helpless in most cases. The participants emphasized that robust information systems connecting all relevant stakeholders are essential. The exploration reveals that the system will not adopt a structured referral method without the government taking interest in it.
Oral diseases are a major contributor to global disability but remain largely neglected in health policy, especially in low- and middle-income countries. India carries a disproportionately high burden of dental caries and periodontal disease, with limited access to oral healthcare and high reliance on out-of-pocket expenditure (OOPE). Despite this, there is a lack of synthesised economic evidence specific to India, which limits informed policymaking and resource allocation. This systematic review aims to assess the economic burden and financial impact of oral diseases in India—at individual, household, health system and societal levels—focusing on direct and indirect costs, including OOPE and catastrophic health expenditure (CHE).
This review will follow the JBI methodology for economic evaluation evidence and adhere to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines. A three-step search strategy will be used to identify relevant studies from databases, including MEDLINE (Ovid), Embase, Scopus, CINAHL (Ovid), Dentistry and Oral Sciences Source (EBSCO) and Cochrane CENTRAL, as well as grey literature sources.
We will include studies conducted in India that report on the economic burden or financial impact of oral diseases at the individual, household or population level. Eligible designs include cost-of-illness studies, cost analysis, cost-outcome analysis and health expenditure analysis using cross-sectional (including repeated cross-sectional) or cohort designs, as well as analyses based on secondary datasets. Studies using econometric, statistical or modelling methods, with or without comparators, will be included. Mixed-methods studies will be eligible if they provide extractable quantitative data.
Two reviewers will independently screen and appraise studies using JBI critical appraisal tools suited to each study design. Data extraction will focus on direct and indirect costs, including OOPE and financial impacts, such as CHE, hardship financing and poverty effects. Findings will be presented narratively and, where feasible, pooled in a meta-analysis using MetaXL V.5 software.
This review does not involve the collection or analysis of individual patient data. Instead, it will use data from publicly available economic research studies. All data sources will be appropriately cited. Extracted data will be systematically curated and managed using version-controlled spreadsheets and reference software. As this is a secondary analysis of published literature, ethical approval is not required. Findings will be disseminated through peer-reviewed publications and scientific presentations, as well as shared with policymakers and community health organisations via policy briefs and stakeholder outreach.
CRD420251030651.
by Ramesh Malashi, Sunita Sharma, Srijana Adhikari, Chitra Raj Sharma, Arun Kumar Joshi, Buna Bhandari
IntroductionHypertension is a significant risk factor for cardiovascular diseases (CVDs), which remains the leading causes of morbidity and mortality globally, with a disproportionate impact on low and middle income countries. While hypertension is prevalent across various populations, government employees are particularly susceptible due to high stress levels, sedentary lifestyles, and work-related pressures. Therefore, this study was undertaken to assess the prevalence of hypertension and its associated risk factors among government employees in the Doti district of Nepal.
MethodsA cross-sectional study was carried out among 195 government employees in Dipayal Silgadhi Municipality of Doti district of Sudurpashchim province of Nepal. The data was collected through face-to-face interviews using Simple Random Sampling (SRS) technique and analysed using SPSS v25. The structured questionnaire adopted from the WHO STEPS survey tool was used for data collection. Bivariate and multivariate logistic regression model was used to assess the factors associated with hypertension.
ResultsThe prevalence of hypertension among government employee was 36.4%% ± 5.6%. Participants with age group 30–40 years [Adjusted Odd’s Ratio (AOR) 14.4, 95% Confidence Interval (CI) (1.6, 127.7)], 40–50 years [AOR 13.7, 95% CI (1.04, 180.3)] and work experience (20–30 years) [AOR 6.67, 95% CI(1.23, 35.9), and drinking alcohol [AOR 0.35, 95% CI (0.17, 0.72)] were found to be statistically significant with hypertension.
ConclusionThe study revealed the high prevalence of hypertension among government employees; significantly associated with risk factors like age group 30–50 years, work experience and alcohol consumption, indicating an alarming public health concern. These results highlight the pressing need for focused interventions to reduce the risk of hypertension and its related problems among government employees, such as lifestyle changes, workplace health programs, and routine health screenings.
Spironolactone is a useful and effective acne treatment option for adult female patients. We aim to establish whether spironolactone could be a safe treatment for the management of acne in the female adolescent population as well. The objective of this scoping review is to provide an evidence map of the safety profile of spironolactone in the paediatric population aged 0–17 across all clinical indications.
This scoping review will be conducted according to the Joanna Briggs Institute scoping review protocol. Relevant publications will be searched on the MEDLINE, Embase and Web of Science databases from inception until July 2025. The authors of included studies will be contacted using contact details provided in the manuscript to check for any further published or unpublished data on the review question. An initial search will be conducted using keywords to identify relevant articles. After identifying the research strategy, articles will be extracted into a reference management tool, and a two-part study selection process will be systematically applied by two reviewers. The first part consists of screening titles and abstracts to define the eligibility of each article. In the second part, the full texts will be screened and only relevant articles will be kept. All articles related to the safety of spironolactone in children and adolescents across all clinical indications will be included. Data will be extracted using a scoping review management software such as Covidence, collated and charted to summarise all the relevant methods, outcomes and key findings in the articles.
This scoping review will provide an extensive overview of the available safety evidence for the use of spironolactone in children and teenagers. Since the scoping review methodology consists of reviewing and collecting data from publicly available materials, this study does not require ethics approval. The results will be disseminated in a peer-reviewed publication.
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