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Remission of type 2 diabetes is achievable in primary care with intensive lifestyle intervention

Por: Zoungas · S. · Sumithran · P.

Commentary on: Hocking SL et al. Intensive Lifestyle Intervention for Remission of Early Type 2 Diabetes in Primary Care in Australia: DiRECT-Aus. Diabetes Care 2024;47:66–70.

Implications for practice and research

  • Intensive lifestyle intervention in primary care can safely achieve type 2 diabetes (T2D) remission at 12 months in around half of selected participants with short-duration, well-controlled T2D.

  • Research on the effectiveness and acceptability of strategies to improve durability of remission is needed.

    • Context

    Although previously thought to be inevitably progressive, evidence is growing that type 2 diabetes (T2D) can be brought into remission with weight loss.

    This study by Hocking et al1 was a single-arm replication of the Diabetes Remission Clinical Trial (DiRECT) randomised controlled trial2 in an Australian setting. It confirms that with an intensive lifestyle intervention including total diet replacement (TDR), around half of adults with recently...
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