This study aims to assess the impact of a protocol-based video education program on nurses' knowledge of medical device-related pressure injuries prevention, self-efficacy in pressure injury care, and satisfaction with the educational program. This study employed a non-equivalent control group pre-test–post-test design. This study was conducted from September 6, 2024, to September 19, 2024. A total of 62 nurses from the integrated nursing care service wards of a general hospital were recruited and divided into 31 experimental and 31 control groups. The experimental group received a one-week protocol-based video education program, whereas the control group received booklet-based education. Both the experimental and control groups demonstrated statistically significant improvements in medical device-related pressure injuries prevention knowledge after the intervention. The interaction effect between group and time was also significant. Self-efficacy scores increased significantly in both the experimental and control groups, although the interaction effect was not statistically significant. Educational satisfaction showed no significant difference between the two groups. The protocol-based video education program effectively improved nurses' knowledge of medical device-related pressure injuries prevention and demonstrated its potential as a repeatable and accessible learning tool. Future research should focus on longer intervention periods, diverse hospital settings, and the inclusion of clinical outcome data such as actual pressure injury incidence to further validate the program's effectiveness.
ClinicalTrials.gov identifier: KCT0010218.