FreshRSS

🔒
☐ ☆ ✇ BMJ Open

Protocol for the development of a global core outcome set for the surgical treatment of sacrococcygeal teratoma in children: a systematic review and international Delphi study

Por: Dongen · M. C. · van Rijn · R. · Sharma · S. · Raphael · M. F. · de Vries · R. · Abouzeid · A. A. · Bugiani · M. · Chirdan · L. B. · van Heurn · E. L. W. · Derikx · J. P. M. · Kremer · M. E. B. · Steering Group · S.-C. — Enero 16th 2026 at 18:44
Introduction

Outcome reporting in studies on sacrococcygeal teratoma (SCT) is highly heterogeneous, which limits comparability across studies and thus hampers the development of international treatment guidelines.

Variation in treatment and access to facilities contributes to differences in outcome reporting between centres and countries. Establishing a Core Outcome Set (COS) can improve consistency in outcome reporting and facilitate global collaboration and data comparison. We therefore aim to develop a Core Outcome Set for SCT (COS-SCT) using the Delphi method to achieve consensus on key outcomes. This will enhance the standardisation of outcome reporting and improve the quality of research and clinical care for SCT patients globally.

Methods and analysis

The development of the COS-SCT will consist of three phases. First, a systematic review will be performed to identify outcomes reported in studies on the surgical treatment of SCT in children. Second, an international Delphi survey will be conducted among key stakeholders, including clinicians, researchers and patient representatives, to establish consensus on outcome prioritisation. Finally, a consensus meeting with representatives from all stakeholder groups will be held to ratify the final Core Outcome Set. The study will follow methodological guidance from the Core Outcome Measures in Effectiveness Trials (COMET) initiative and will be developed and reported in accordance with the Core Outcome Set Standards for Development (COS-STAD) and Core Outcome Set Standards for Reporting (COS-STAR).

Ethics and dissemination

The medical research ethics committee of the Amsterdam University Medical Centre (Amsterdam UMC) confirmed that the Dutch Medical Research Involving Human Subjects Act (WMO) does not apply to this study, and therefore a full review by the ethics committee is not required. This study is registered in the COMET initiative database. Results will be disseminated in peer-reviewed academic journals and conference presentations.

Trial registration number: COMET registration number 3485

☐ ☆ ✇ BMJ Open

Traditional, integrative and complementary medicine use in the UK population: results of a nationally representative cross-sectional survey

Por: van der Werf · E. T. · Foley · H. · Carter · T. · Roberts · R. · Adams · J. · Steel · A. — Enero 16th 2026 at 18:44
Objectives

To describe the prevalence and characteristics of traditional, complementary and integrative medicine (TCIM) practice and product use by the population of the UK providing up-to-date data on the landscape of TCIM use in the UK.

Design, setting and participants

A cross-sectional online survey, administered using the Qualtrics platform, among adults (aged 18 years and over) residing in the UK (England, Wales, Scotland or Northern Ireland). Data were collected between May and October 2024. The 40-item instrument covered four domains: demographics, health status, use of health products and practices, and use of health services. Descriptive statistics were used to summarise survey responses, and ² tests were applied to assess associations between participant characteristics and TCIM use. Backwards stepwise logistic regression was conducted to identify predictors of TCIM use across four outcome categories (p≤0.05).

Results

The sample (n=1559) was broadly representative of the UK population. Prevalence of any TCIM use over a 12-month period was 65.9% with 19.1% consulting a TCIM practitioner and 63.3% using any TCIM product or practice. Bodywork therapists (massage therapists 9.4%, chiropractors 7.9%, yoga teachers 5.0%) and homeopaths (4.1%) were the most commonly consulted TCIM practitioners and Anthroposophic doctors were the least commonly consulted (2.1%). Among TCIM products, vitamin and mineral supplements were the most commonly used (37.3%) and relaxation or meditation practices were reported by 19.4% of respondents. TCIM users were more likely to be female, identify as Asian or Black, have a chronic disease diagnosis, report good health, possess private health insurance, have a higher education level, be employed (or seeking employment) and sometimes experience financial management difficulties.

Conclusions

There is substantial use of TCIM across the UK adult population and there is a need for more research on integrating TCIM into mainstream healthcare and the National Health Service. Clear strategies are necessary to enhance communication between TCIM and conventional healthcare providers, ensure patient safety and promote person-centred, coordinated models of care.

☐ ☆ ✇ Journal of Advanced Nursing

Nurse Practitioner‐Sensitive Outcome Measures in Older Person Care: A Scoping Review

ABSTRACT

Background

Nurse practitioner-sensitive outcomes (NPSOs) are critical indicators of the quality and effectiveness of nursing care provided to older adults. These outcomes, which include metrics such as falls, pressure ulcers, infection rates, frailty, delirium, length of stay, hospital readmissions, and quality of life (QoL), are essential for assessing the impact of nurse practitioners (NPs) and enhancing patient safety. Despite their importance, the current literature on NPSOs in services for older adults remains limited. This scoping review aims to address this gap by systematically mapping the existing research, identifying key themes, and uncovering areas needing further exploration. By doing so, the authors seek to provide a comprehensive overview that will inform future research directions and contribute to the enhancement of clinical practice in older person services (OPS). This review is important for healthcare providers, policymakers, and researchers who are committed to improving the quality of nursing care and outcomes for older people.

Aim

The aim of this scoping review is to map the existing research on NPSOs in services for older adults. This review seeks to identify key themes and gaps in the current literature to guide future research and enhance clinical practice in this area.

Method

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) guidelines were utilised to structure this scoping review.

Results

From initial screening of 3593 manuscripts drawn from seven databases, 66 were deemed eligible for full screen. Five studies met the inclusion criteria and were ultimately selected for data extraction and analysis. The most common outcome measures reported were complications and comorbidities, and QoL.

Conclusions

This review highlights that the reporting of NPSOs in older person care is lacking and requires further attention.

☐ ☆ ✇ Journal of Advanced Nursing

Obstacles and Aspirations for Improving Delivery of Cardiopulmonary Resuscitation to Wheelchair Users: A Qualitative Study

Por: Elisha Deegan · Peter Lewis · Nathan Wilson · Laynie H. Pullin — Enero 16th 2026 at 16:16

ABSTRACT

Aim

To describe obstacles and ideas for improvement for the delivery of cardiopulmonary resuscitation and basic life support to wheelchair users.

Design

A descriptive qualitative study underpinned by constructivism was conducted.

Methods

Semi structured interviews were completed with 26 participants from three cohorts: formal and informal carers, wheelchair users and healthcare professionals. Data were collected via online and in person interviews between February and June 2024. All participants were located in Australia, with the exception of one who was located in the United Kingdom. Data were analysed using thematic analysis.

Results

Two major themes were identified: (1) obstacles to providing cardiopulmonary resuscitation and basic life support to a wheelchair user and (2) aspirations for improving cardiopulmonary resuscitation and basic life support for wheelchair users.

Conclusion

Participants shared ideas for how to improve emergency care for wheelchair users, highlighting a need for further research, testing and development of an education intervention.

Implications for the Profession and/or Patient Care

Improving knowledge about providing emergency care to a wheelchair user could improve outcomes, save lives and reduce the life expectancy gap experienced by people with disability.

Impact

Approximately 2% of the global population use a wheelchair. Wheelchair use complicates the delivery of cardiopulmonary resuscitation and basic life support. There are currently no guidelines informing emergency care for wheelchair users available globally. Recognition of common symptoms of distress exhibited by wheelchair users, and options for the delivery of practical emergency care are required for wheelchair users.

Reporting Method

The paper adheres to the EQUATOR reporting guidelines utilising the SRQR checklist.

Patient or Public Contribution

Patients and the public were the driving force in recognising the gap in knowledge regarding the delivery of CPR to wheelchair users. Questions from patients and the public shaped the aims and methodological choices for this study.

☐ ☆ ✇ Journal of Advanced Nursing

Experiences of Nurses With Power‐Structures in Hospital Care: A Qualitative Study

ABSTRACT

Aim

To explore nurses' experiences with power structures in hospital care and to develop policy recommendations for transforming disempowering structures.

Design

A three-phased critical ethnographic design.

Method

Data were collected in a general teaching hospital in the Netherlands between December 2022 and June 2024 through (1) ethnographic diaries kept by nurses, (2) semi-structured interviews, (3) partial participant observations, (4) one focus group discussion with only nurses and (5) one multistakeholder focus group. Thematic analysis was used to identify themes.

Findings

Twenty-eight nurses of thirteen different departments and nine stakeholders participated. Four themes emerged from the analysis: (1) power in cooperation, (2) hierarchical relationships, (3) aggression and (4) insufficient decision-making power in hospital policies. The first theme was experienced as an empowering structural condition, while the last three were identified as disempowering structures.

Conclusion

Job satisfaction and quality of care among nurses are at risk and elicit feelings of burnout because of nurse–doctor hierarchies, aggression and insufficient decision-making power in hospital policies. Therefore, improving interprofessional cooperation and including nurses in decision-making is crucial to structurally empower nurses.

Implications

Hospital administrators need to create empowering conditions for nurses by furthering inclusion in policy making and setting department goals, implementing interprofessional education for effective collaboration, increasing nurse representation throughout hospital management layers and ensuring strong support systems. These interventions are important in addressing aggression, hierarchies, nurse turnover and burnout.

Reporting Method

COREQ guidelines were used for reporting qualitative studies.

Patient or Public Contribution

None.

☐ ☆ ✇ Journal of Advanced Nursing

Factors Affecting the Quality of Life of Parents of Children With Spina Bifida: The Mediating Role of Family Resilience

Por: Kyua Kim · Hyeseon Yun · Hooyun Lee · Kijun Song · Marcia Van Riper · Eun Kyoung Choi — Enero 16th 2026 at 16:16

ABSTRACT

Aims

To investigate factors affecting the quality of life of parents of children with spina bifida and examine how family resilience mediates between parental depression and quality of life.

Design

Cross–sectional study.

Methods

Secondary data analysis was performed using first-year data from a five-year spina bifida cohort project (2022–2026) in South Korea. The study included 162 parents of children aged 4–12 years with spina bifida. Data were collected using the Korean version of the Family Resiliency Scale, the Center for Epidemiologic Studies Depression Scale, and the WHO Quality of Life Scale.

Results

Factors were found to have a statistically significant influence on the quality of life of parents of children with spina bifida: the child's need for enemas, parental stress, parental depression, and family resilience. Baron & Kenny's mediation analysis and bootstrap analysis in SPSS further confirmed that family resilience plays a mediating role between parental depression and quality of life. The indirect effect of parental depression on quality of life through family resilience was statistically significant, with a 95% confidence interval of [−0.2615, −0.0516].

Conclusion

The quality of life of parents with children with spina bifida is significantly influenced by both their child's daily symptom management and their psychological health. Family resilience plays a positive mediating role between parental depression and quality of life.

Implications for the Profession and/or Patient Care

These findings support a two-track approach to family resilience building programs and the development of core intervention strategies to enhance the quality of life in spina bifida families.

Reporting Method

This study adhered to Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines.

Patient Contribution

There was no direct patient involvement in the study design, data collection, or analysis.

☐ ☆ ✇ Journal of Advanced Nursing

Clinical Supervision Practices With Australian Child and Family Health Nurses: Exploring Facilitators and Barriers

Por: Anne O'Neill · Leesa Hooker · Kristina Edvardsson — Enero 16th 2026 at 16:16

ABSTRACT

Aim

To explore Australian Maternal and Child Health nurses' clinical supervision practice and barriers and facilitators to effective supervision.

Methods

An online survey was distributed to all nurses and managers in Victoria, Australia.

Results

A total of 188 MCH nurses responded to the survey, and of these, 147 completed the 26-item version of the validated Manchester Clinical Supervision Scale. Data were analysed using descriptive statistics. The majority of nurses (91%) received facilitated group supervision, and most nurses (86%) were moderately or very satisfied with their clinical supervision. In total, 81% of nurses perceived clinical supervision to be of benefit according to the Manchester Clinical Supervision Scale-26 results. Open text responses were analysed according to barriers, facilitators and general comments. Key facilitators included supervisors with group facilitation skills and support for reflection. Barriers to effective supervision related to group dynamics, insufficient time and varied understanding of the purpose of sessions among participants.

Conclusion

Effective clinical supervision relies on the establishment of clear aims and shared understandings among participants, skilled facilitation and managerial support.

Impact

Clinical supervision can facilitate reflective practice and learning when implemented as intended. This study highlights the role of professional nursing bodies, service providers and educational institutes to raise awareness of the conditions needed to achieve this.

Reporting Method

Complies with Equator Guideline (STROBE).

Patient or Public Contribution

No patient or public contribution.

☐ ☆ ✇ Journal of Advanced Nursing

Association Between Nursing Workload and Intensive Care Unit Readmissions: A Prospective Cohort Study

ABSTRACT

Aim

The aim of this study was to assess the relationship between nursing workload at the time of intensive care unit discharge and the likelihood of intensive care unit readmission.

Design

This single-center prospective cohort study was conducted at a Belgian academic hospital and included all intensive care unit admissions from June 1, 2021 to May 31, 2022.

Methods

The Nursing Activities Score was documented by the nurse responsible for each patient during every shift. Adult patients (≥ 18 years) with intensive care unit stay exceeding 24 h during the study period were eligible for inclusion. Those discharged to another hospital, a nursing home, or their own home were excluded due to the inability to ensure follow-up.

Results

Among the 1293 eligible admissions recorded during the study period, 133 patients (10.3%) experienced readmission. Readmitted patients exhibited a higher prevalence of medical reasons for intensive care unit admission, significantly increased mortality rates, and longer hospital length of stay compared to non-readmitted patients. The average daily Nursing Activities Score did not differ significantly between the two groups. The Nursing Activities Score at intensive care unit discharge was notably higher in readmitted patients, and those with a score above the median at discharge demonstrated an increased risk of readmission within 30 days. In multivariable analysis, a high Nursing Activities Score at intensive care unit discharge was an independent predictor of readmission.

Conclusions

An elevated nursing workload, as indicated by the Nursing Activities Score recorded at intensive care unit discharge, was significantly associated with a higher risk of readmission.

Implications for the Profession and/or Patient Care

The study examines the relationship between nursing workload at the time of ICU discharge and the likelihood of unplanned readmission. The results highlight the critical role of nursing workload assessment at ICU discharge in capturing the complexity of care requirements patients face at discharge. The results emphasise the importance of revising discharge planning processes, identifying nursing workload as a critical factor in unplanned readmissions.

Reporting Method

STROBE guidelines were used for this study.

Patient or Public Contribution

Not applicable.

☐ ☆ ✇ Journal of Advanced Nursing

A Neonatal Nurse‐Controlled Model of Analgesia to Manage Post‐Operative Pain in the Surgical Neonate: A Pilot Randomised Controlled Trial

Por: Renee Muirhead · Kathryn Kynoch · Glenda Hawley · Emma Ballard · Pita Birch · P. A. Lewis — Enero 16th 2026 at 16:16

ABSTRACT

Aim

To test the feasibility and acceptability of a newly developed model of neonatal nurse-controlled analgesia to manage pain in the post-operative infant.

Design

The study utilised a single-centre two-arm parallel, unblinded randomised controlled external pilot trial design.

Methods

The pilot trial was conducted in a surgical neonatal tertiary intensive care unit in Brisbane, Australia. Eligible infants were randomised to receive either post-operative pain management care via a model of neonatal nurse-controlled analgesia or standard care. Feasibility and acceptability were the primary outcomes. Seven feasibility outcomes were assessed by a traffic light system to delineate progression to a larger trial. Acceptability and clinical utility of the model of care by staff were assessed by feedback from an anonymous questionnaire that was administered at the completion of the trial period. Secondary outcomes included parental attitudes and perceptions of post-operative pain management to help establish primary outcomes for a larger randomised controlled trial.

Results

Overall staff found the formalised model beneficial for managing post-operative pain but found the complexity of the model and ability to titrate analgesia based only on documented pain scores barriers requiring further consideration. Three of the seven feasibility outcomes failed to reach ‘greenlight’ targets to progress to a larger trial with adherence to the model, and the proportion of eligible infants not recruited was allocated a ‘redlight’. Secondary outcomes were comparable and support future study.

Conclusion

This pilot feasibility study has shown that a model of neonatal nurse-controlled analgesia can be safely implemented and utilised in the post-operative care of the surgical neonate. Further exploration of the barriers to model adherence and recruitment is warranted before a future larger trial is undertaken.

Impact

Though not all primary outcomes reached an acceptable range for further progression, this pilot feasibility study provided invaluable learning and has provided direction for future research into the provision of a family integrated and responsive model of analgesia.

Reporting Method

This study is reported in line with the Consolidated Standards of Reporting Trials (CONSORT): Extension to randomised pilot and feasibility trial and the TIDieR Checklist (Template for Intervention, Description and Replication).

Public or Patient Contribution

No patient or public contribution was utilised for this study.

Trial Registration: ACTRN12623000643673—the trial was prospectively registered

☐ ☆ ✇ Journal of Advanced Nursing

Palliative Care for People With Very Severe to Extreme Behavioural and Psychological Symptoms of Dementia (BPSD): A Scoping Review

Por: Maree Gallop · Jenny Ford · Alexandra Bowman · Antony Mullen · Debbie Schwebel · Amanda Johnson · Ritin Fernandez — Enero 16th 2026 at 16:16

ABSTRACT

Aim

To explore current evidence regarding the provision of palliative care for individuals with very severe to extreme behavioural and psychological symptoms of dementia (BPSD) in a hospital setting.

Design

Scoping review.

Reporting Method

The PRISMA-ScR reporting guideline.

Methods

The JBI guidelines for scoping reviews were followed. A data extraction form assisted in the identification of key findings via a process of content analysis.

Data Sources

Studies were obtained from bibliographic databases of PubMed, CINAHL, and PsycINFO.

Results

This review included six articles, and nine categories emerged from the findings. Symptom assessment and management, pain assessment challenges, atypical presentation of end-stage dementia, complex prescribing and treatment practices, principles of person-centred care, collaboration; training for health care professionals; emotional impact on staff; and family and caregivers.

Conclusions

This scoping review highlighted a significant gap in the literature regarding palliative care for people living with very severe to extreme BPSD in hospital settings. This review highlighted key differences in the presentation of people with BPSD needing palliative care. There is a need for tailored models of care, specialised training and education for health professionals, families, and carers, and recognition of dementia as a terminal illness.

Implications for the Profession and/or Patient Care

The results of this review provide valuable insights into the level of understanding about the unique palliative care needs for people experiencing very severe to extreme BPSD, making an important contribution to the planning and development of future models of care.

Impact

Mapping the available literature highlights a paucity of research in palliative care for people with very severe to extreme BPSD in hospital settings. There is a need for rigorous research studies and models of care developed and informed by the evidence for this small population necessitating unique care needs.

Patient or Public Contribution

No patient or public contribution.

☐ ☆ ✇ PLOS ONE Medicine&Health

The mediating role of internal motivation on the relationship between ethical leadership and employee performance in hospitals in Northern Jordan

Por: Raya Al-Bataineh · Ameera Hayajneh — Enero 16th 2026 at 15:00

by Raya Al-Bataineh, Ameera Hayajneh

Objective

The study’s main aim is to investigate the influence of ethical leadership (EL) on employee performance (EP) through internal motivation (IM) from the perspectives of clinical and administrative employees working in hospitals in northern Jordan.

Method: Design

The study used a descriptive, correlational cross-sectional quantitative design.

Participants and setting

Data were collected from 330 clinical and administrative employees between February and March 2024 using convenience sampling from five hospitals—2 public, 2 private, and 1 teaching hospital—in different geographical areas in northern Jordan. The study hypotheses were tested using a hierarchical multiple linear regression.

Results

The study results revealed a statistically significant association between ethical leadership, internal motivation, and employee performance. Moreover, the results showed that internal motivation statistically mediates the relationship between ethical leadership and employee performance.

Conclusion

The current study’s findings can serve as an empirical basis for hospital decision-makers to plan and implement programs and/or establish or revise policies for the target population, improving employees’ performance, achieving desired outcomes, and ultimately providing better care for patients.

☐ ☆ ✇ PLOS ONE Medicine&Health

Custom foot orthoses for chronic metatarsalgia: Study protocol for a participant- and assessor-blinded superiority randomized controlled trial

by Eléna Payen Schalkens, Maxime Acien, Andrée-Anne Marchand, Pier-Luc Isabelle, Jacques Abboud, Gabriel Moisan

Background

Chronic metatarsalgia (CM) causes significant pain and disability, affecting quality of life. Foot orthoses (FOs) including medially wedged designs with a metatarsal pad decrease excessive plantar pressure under the metatarsal heads, which is a suggested risk factor for developing CM. This FOs model may be effective in diminishing pain and improving function in these individuals. Thus, the objective of this trial will be to compare the effects of medially wedged FOs with a metatarsal pad and sham FOs on pain and foot function in individuals with CM.

Methods/design

This participant- and assessor-blinded superiority randomized controlled trial (RCT) with two parallel groups will be conducted in Trois-Rivières, Canada. Sixty-four participants with CM will be recruited from the Université du Québec à Trois-Rivières outpatient podiatry clinic and via social media invitations. They will be randomized into intervention (customized FOs) or control (sham FOs) groups and will be evaluated at baseline and after 6 and 12 weeks. The primary outcome will be: (1) mean pain during walking for the most painful foot during the past week. The secondary outcomes will be: (1) Foot Function Index, (2) Global rating of change and (3) the 5-level EQ-5D.

Discussion

Medially wedged FOs with a metatarsal pad are expected to provide a greater reduction in pain and improvement in foot function compared to sham FOs. This trial will help guide FOs prescription recommendations for managing foot pain in individuals with CM in the future.

Trial registration

ClinicalTrials.gov NCT06962475

☐ ☆ ✇ PLOS ONE Medicine&Health

Towards practical AI for agriculture: A self-supervised attention framework for Spinach leaf disease detection

by Nilavro Das Kabya, MD Shaifullah Sharafat, Rahimul Islam Emu, Mehrab Karim Opee, Riasat Khan

Malabar spinach is a nutrient-dense leafy vegetable widely cultivated and consumed in Bangladesh. Its productivity is often compromised by Alternaria leaf spot and straw mite infestations. This work proposes an efficient and interpretable deep learning framework for automatic Malabar spinach leaf disease classification. A curated dataset of Malabar spinach images collected from Habiganj Agricultural University and supplemented with public samples was categorized into three classes: Alternaria, straw mite, and healthy leaves. A lightweight SpinachCNN established a strong baseline, while Spinach-ResSENet, enhanced with squeeze-and-excitation modules, improved channel-wise attention and feature discrimination. A customized Vision Transformer (SpinachViT) and SwinV2-Base were further investigated to assess the benefits of transformer-based architectures under limited data. To mitigate annotation scarcity, we employed SimSiam-based self-supervised pretraining on unlabeled images, followed by supervised fine-tuning with cross-entropy or a hybrid objective combining cross-entropy and supervised contrastive loss. The best-performing domain-optimized model, SimSiam-CBAM-ResNet-50, incorporated Convolutional Block Attention Modules and achieved 97.31% test accuracy, 0.9983 macro ROC-AUC, and low calibration error, while maintaining robustness to Gaussian and salt-and-pepper noise. Although a SwinV2-Base benchmark pretrained on ImageNet-22k reached slightly higher accuracy (97.98%, 98.99% with test-time augmentation), its 86.9M parameters and reliance on large-scale pretraining reduce feasibility for edge deployment. In contrast, the SimSiam-CBAM model offers a more parameter-efficient and deployment-friendly solution for real-world agricultural applications. Model decisions are interpretable via Grad-CAM, Grad-CAM++, and LayerCAM, which consistently highlight biologically relevant lesion regions. The spinach dataset used in this study is publicly available on: https://huggingface.co/datasets/saifullah03/malabar_spinach_leaf_disease_dataset.
☐ ☆ ✇ BMJ Open

Trajectory, healthcare utilisation and recovery in 3590 individuals with long covid: a 4-year prospective cohort analysis

Por: Prashar · J. · Hillman · T. · Wall · E. C. · Sarna · A. · Mi · E. · Bell · R. · Sahota · J. · Zandi · M. · McNamara · P. · Livingston · R. · Gore · R. · Lunken · C. · Bax · E. · Nyam · R. · Rafie Manzelat · A. M. · Hishmeh · L. · Attree · E. · Cone · S. · Banerjee · A. · Heightman · M. — Enero 14th 2026 at 15:37
Objective

To characterise long-term trajectory of recovery in individuals with long covid.

Design

Prospective cohort.

Setting

Single-centre, specialist post-COVID service (London, UK).

Participants

Individuals aged ≥18 years with long covid (hospitalised and non-hospitalised) from April 2020 to March 2024.

Main outcome measures

Routine, prospectively collected data on symptoms, quality of life (including Fatigue Assessment Scale (FAS) and EuroQol 5 Dimensions (EQ-5D), return to work status and healthcare utilisation (investigations, outpatient and emergency attendances). The primary outcome was recovery by self-reported >75% of ‘best health’ (EQ-5D Visual Analogue Scale) and was assessed using Cox proportional hazards regression models over 4 years. Linked National Health Service England registry data provided secondary care healthcare utilisation and expenditure.

Results

We included 3590 individuals (63.3% female, 73.5% non-hospitalised, median age 50.0 years, 71.9% with ≥2 doses of COVID-19 vaccination), who were followed up for a median of 136 (0–346) days since first assessment and 502 (251–825) days since symptom onset. At first assessment, 33.2% of employed individuals were unable to work. Dominant symptoms were fatigue (78.7%), breathlessness (68.1%) and brain fog (53.5%). 33.4% of individuals recovered to >75% of best health prior to clinic discharge (recovery occurred median 202 (94–468) days from symptom onset). Vaccinated individuals were more likely to recover faster (pre: HR 2.93 (2.00–4.28) and post: HR 1.34 (1.05–1.71) COVID-19 infection), whereas recovery hazard was inversely associated with FAS (HR 0.37 (0.33–0.42)), myalgia (HR 0.59 (0.45–0.76)) and dysautonomic symptoms (HR 0.46 (0.34–0.62)). There was high secondary care healthcare utilisation (both emergency and outpatient care). Annual inpatient and outpatient expenditure was significantly lower in hospitalised individuals while under the service. When compared with the prereferral period, emergency department attendances were reduced in non-hospitalised patients with long covid, but outpatient costs increased.

Conclusions

In the largest long covid cohort from a single specialist post-COVID service to date, only one-third of individuals under follow-up achieved satisfactory recovery. Fatigue severity and COVID-19 vaccination at presentation, even after initial COVID-19 infection, was associated with long covid recovery. Ongoing service provision for this and other post-viral conditions is necessary to support care, progress treatment options and provide capacity for future pandemic preparedness. Research and clinical services should emphasise these factors as the strongest predictors of non-recovery.

☐ ☆ ✇ BMJ Open

Nutritional knowledge, attitudes and practices and their determinants among pregnant women attending healthcare centres in southern Tehran

Por: Rajaeieh · G. · Bakhtiari · A. · Gholami · M. · Ghavidel · F. · Mostafavi · H. · Zabihi · M. · Mohamadi · E. · Olyaeemanesh · A. · Takian · A. — Enero 14th 2026 at 15:37
Objectives

To assess nutrition-related knowledge, attitudes and practices among pregnant women, and identify socioeconomic and healthcare determinants.

Design

A cross-sectional study on maternal nutrition during pregnancy.

Setting

Pregnant women attending primary healthcare centres in the south of Tehran from December 2022 to March 2024.

Participants

1535 pregnant women of all ages living in the south of Tehran (both Iranian and non-Iranian).

Measures

Pregnant women were systematically selected from primary healthcare centres. Data were collected via validated questionnaires and electronic health records. Statistical analyses included multivariate logistic regression (adjusted ORs (aORs) with 95% CIs) and generalised linear mixed models.

Results

The findings revealed that a majority of pregnant women (83.3%; 95% CI 81.2% to 85.3%) exhibited low levels of nutritional knowledge (scores below 12), whereas 14% demonstrated moderate knowledge (scores between 12 and 17), and only 2.7% (95% CI 1.9% to 3.8%) possessed high nutritional knowledge (scores above 18). In terms of attitudes, 36.9% of respondents expressed positive views toward nutrition, with higher education significantly associated with positive attitudes (aOR=1.8; 95% CI 1.3 to 2.5, comparing higher vs lower education levels). Dietary variety was consistently reported by 65.4% of participants, while 8.5% lacked dietary variety. Statistically significant associations were observed between educational attainment, socioeconomic status and nutrition-related practices (p

Conclusion

As a cross-sectional study, these findings highlight substantial gaps in nutrition knowledge among pregnant women in Tehran, with socioeconomic status and education playing crucial roles in shaping dietary behaviours. Improving nutritional education through healthcare interventions is essential for enhancing maternal and fetal health outcomes.

☐ ☆ ✇ Journal of Nursing Scholarship

Social Determinants of Health and Falls Among Community‐Dwelling Older Adults: A Zero‐Inflated Negative Binomial Regression Analysis

Por: Eunjin Kim · Dahee Wi · Jiae Lee · Chang Park · Yoonjung Kim — Enero 14th 2026 at 11:45

ABSTRACT

Introduction

Falls among older adults represent a major public health challenge, yet research examining the role of social determinants of health (SDOH) in fall risk remains limited. This study aimed to identify factors associated with fall occurrence and fall frequency among community-dwelling older adults in Korea, with particular emphasis on SDOH.

Design

A cross-sectional study design.

Methods

We used a large nationwide sample (n = 9746) from the 2023 National Survey of Older Koreans. The number of falls in the past year served as the dependent variable. Independent variables included a range of socioeconomic and environmental variables as SDOH, alongside biological and behavioral variables. A zero-inflated negative binomial (ZINB) regression analysis was employed to address excess zeros and overdispersion in fall count data.

Results

Among participants, 94.8% experienced no falls, 3.2% reported a single fall, and 1.9% reported recurrent falls. In the logit model for fall occurrence, higher household income level, absence of age-friendly housing, higher access to parks, and lower access to welfare centers were associated with higher risk of fall occurrence. In the count model for fall frequency, higher education level, presence of age-friendly housing, and outdoor mobility barriers were associated with higher fall frequency within the at-risk group.

Conclusions

The findings provide empirical evidence on the critical roles of SDOH in falls among community-dwelling older adults. Specifically, a ZINB regression analysis identified distinct sets of SDOH associated with fall occurrence versus fall frequency, highlighting the complex and multifaceted nature of fall patterns among older adults.

Clinical Relevance

Healthcare providers and policymakers seeking to reduce falls should implement tailored, SDOH-integrated strategies by addressing the different mechanisms underlying fall occurrence and fall frequency.

☐ ☆ ✇ BMJ Open

Complications and costs to the UK National Health Service due to outward medical tourism for elective surgery: a rapid review

Por: England · C. · Bromham · N. · Needham-Taylor · A. · Hounsome · J. · Gillen · E. · Ingram · B.-J. · Davies · J. · Edwards · A. · Lewis · R. — Enero 13th 2026 at 23:31
Objectives

Outward medical tourism is when people seek medical treatment in a different country to the one they live in. We aimed to identify all studies that describe the impact on the UK National Health Service (NHS) of patients who require treatment due to outward medical tourism for elective surgery and report on complications, costs and benefits.

Design

A rapid literature review. Medical and grey literature databases were searched, limited to literature published between 2012 and 2024.

Selection criteria

Studies published in the English language, conducted in any NHS setting, describing complications, costs or benefits due to outward medical tourism for elective surgery were included. We excluded emergency and semi-urgent surgery, dental and transplant surgery, cancer treatment and fertility treatment.

Outcome measures

Primary outcomes were costs and savings to the NHS. Secondary outcomes were type and frequency, demographics, procedures, complications, treatment, follow-up care and use of NHS resources. Results were summarised narratively. Study quality was assessed using JBI critical appraisal tools and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used for certainty of evidence for costs.

Results

Some 35 case series and case reports and two surveys of NHS plastic surgeons were identified. Case studies described 655 patients treated in specific NHS hospitals between 2006 and 2024 for postoperative complications due to metabolic/bariatric surgery (n=385), cosmetic (n=265) and ophthalmic (n=5) surgery tourism. No cases relating to other surgical specialities were identified in the literature. Most patients were women (90%), with an average age of 38 (range 14–69) years. The most common destination for surgery was Turkey (61%). Complications were not well described for metabolic/bariatric surgery tourism; but for cosmetic surgery tourism, infection and wound dehiscence were most commonly reported. There was evidence that some patients needed complex treatment involving long hospital stays and multiple surgical interventions. Very low certainty evidence indicated that costs to the NHS from outward medical tourism for elective surgery ranged from £1058 to £19 549 per patient in 2024 prices. We found no studies that reported on the benefits of outward medical tourism.

Conclusions

A systematic approach is needed to collecting information on the number of people who travel abroad for elective surgery and the frequency and impact on the UK NHS of treating complications. Without these data, we cannot fully understand the risk of seeking surgery abroad.

☐ ☆ ✇ BMJ Open

Attitudes of maternity care providers toward regional centralisation of vaginal breech birth: a qualitative study

Por: Luiting-Wagenaar · D. · van Dijk · M. · Ganzevoort · W. · Moll · E. · Scheele · F. · Velzel · J. — Enero 13th 2026 at 15:20
Objectives

To explore maternity care providers’ attitudes toward regional centralisation of vaginal breech birth (VBB) care and gather their recommendations for maintaining clinical proficiency.

Design

Exploratory qualitative study using semi-structured interviews and thematic analysis.

Participants

10 hospital-based maternity care professionals (nine obstetricians and one clinical midwife), purposively sampled to represent experience and institutional diversity.

Setting

10 hospital maternity units in a metropolitan region of the Netherlands.

Key themes describing provider attitudes towards two proposed models of centralised care (mobile breech team, designated referral centre) and alternative strategies.

Results

Three core themes emerged: (1) proficiency—providers valued regular exposure, formal training and peer support, expressing concern that centralisation would reduce overall workforce readiness; (2) organisation—concerns included unequal access, staffing burden, legal risks and inefficiencies in mobile teams and (3) alternatives—participants preferred a regional breech network with shared training, joint video review and expert on-call support.

Conclusions

Maternity care providers opposed full centralisation of VBB, favouring a networked model that distributes expertise and preserves local access. These insights highlight the importance of involving frontline providers in service redesign.

Trial registration number

Not applicable.

☐ ☆ ✇ BMJ Open

The journey to healing: exploring travel challenges and associated costs for cancer care at a tertiary care centre in Puducherry, Southern India - a mixed methods study

Por: Devaraj · L. · Ayiraveetil · R. · Arikrishnan · K. · Sahu · S. K. · Ganesan · P. · Karunanithi · G. · Auroprem · S. P. · Srinivasan · T. S. · Thulasingam · M. — Enero 13th 2026 at 15:20
Objectives

This study aims to assess travel time, associated costs, challenges and factors influencing healthcare facility choices among persons with cancer in Southern India.

Design

An explanatory sequential mixed methods study.

Setting

The study was conducted in the cancer care outpatient department at a tertiary care centre in Puducherry, Southern India.

Participants

A total of 192 persons with cancer aged 18 to 65 years, diagnosed with breast, lip and oral cavity, cervical, lung or upper gastrointestinal cancers, and attending the cancer care centre between 2023 and 2024, were enrolled in the study through systematic random sampling. Additionally, 10 in-depth interviews were conducted using purposive sampling.

Results

Of the 192 participants, 89 (46.4%) belonged to a lower socioeconomic group, and 178 (92.7%) reported experiencing financial hardship while undergoing cancer treatment. The median travel time to a tertiary care centre was 4.3 hours (IQR: 2.07–7.3), with a median direct non-medical cost of Indian Rupees (INR) 453 (IQR: 200–987). Median expenditures for travel, food and accommodation were INR 200 (IQR: 123–400), INR 360 (IQR: 150–613) and INR 30 (IQR: 20–60), respectively, per single visit. A significant proportion of participants (n=146, 76%) were unaware of nearby cancer treatment centres and relied on peer recommendations when choosing their place of treatment. Key challenges identified included long-distance travel, financial burden due to high food and transportation costs and limited affordability for accommodation.

Conclusion

The study highlights that prolonged travel time and associated costs pose substantial financial strain on cancer-affected families. Enhancing awareness of available healthcare facilities, implementing patient-friendly travel and accommodation support systems and decentralising cancer care services can improve accessibility and mitigate both travel and financial burdens.

❌