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☐ ☆ ✇ Evidence-Based Nursing

Behaviours as biomarkers? Disentangling causality between vitamin D, sedentary behaviours and mortality is necessary for preventing recurrence and cardiovascular disease in cancer survivors

Por: Giorgi Rossi · P. · Bonvicini · L. — Junio 19th 2025 at 10:25

Commentary on: Yu Y, Cheng S, Huang H, et al. Joint association of sedentary behaviour and vitamin D status with mortality among cancer survivors. BMC Med 2023;21:411.

Implications for practice and research

  • Results support National Institute for Health and Care Excellence recommendations7 in defining vitamin D levels below 50 nmol/L as insufficient and highlight sitting time over 6 hours/day as a possible determinant of mortality in cancer survivors.

  • Biological mediators linking sedentary behaviours, vitamin D and health outcomes should be investigated to understand the underlying causal link.

  • Context

    Many observational studies showed that sedentary behaviours1 and low serum levels of vitamin D2 are independent risk factors for mortality in cancer survivors. Nevertheless, data from trials on vitamin D supplementation3 and interventions promoting physical activity4 did not obtain the effect on mortality in cancer survivors that...

    ☐ ☆ ✇ Journal of Clinical Nursing

    Being a nurse between research and clinic: What challenges and opportunities for a PhD‐prepared nurse? Overview from an Italian paediatric hospital

    Abstract

    Aim

    To report a reflection on the role, challenges and opportunities for nurses with advanced education in research outside the academic field.

    Design

    A discursive paper.

    Data Sources

    We reported the case of an Italian paediatric research hospital where PhD-prepared nurses started to apply their knowledge and competencies in different fields, both in clinical and organizational settings. From this experience, an overview of the possible barriers and challenges that PhD-prepared nurses may face up within the hospital setting.

    Discussion

    The application of PhD-prepared nurses in hospital settings could be an opportunity to advance high standards of quality of care in managerial and clinical areas and to create networks between highly specialized professional figures and different clinical-care realities.

    Conclusion

    More research is needed to explore how to apply the advanced competencies of PhD-prepared nurses within healthcare organizations to provide high-quality and safe care and services.

    This paper can provide insights for a reflection on applying and developing PhD-prepared nurses' skills and competencies within the hospital setting in clinical, research and managerial areas. This can enhance the effective application of highly competent nursing professional figures.

    Patient or Public Contribution

    No Patient or Public Contribution, due to study design.

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